Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Interleukin-33 (IL-33), a member of the IL-1 cytokine family and a multifunctional cytokine,
plays critical roles in maintaining host homeostasis and in pathological conditions, such as …

INTRODUCTION Obesity and its associated complications are serious global concerns.
Despite growing public health initiatives, obesity rates continue to rise. Thus, there is a …

The release of cytokines from epithelial and stromal cells is critical for the initiation and
maintenance of tissue immunity. Three such cytokines, thymic stromal lymphopoietin, IL-33 …

Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells through a process
that is primarily mediated by T cells. Emerging evidence suggests that dendritic cells (DCs) …

Interleukin-33 (IL-33) is a cytokine defined by its pleiotropic function, acting either as a
typical extracellular cytokine or as a nuclear transcription factor. IL-33 and its receptor …

Recruitment of regulatory T cells (Tregs) to tumors is a hallmark of cancer progression.
Tumor-derived factors, such as the cytokine thymic stromal lymphopoietin (TSLP), can …

Type 2 immune responses commonly emerge during allergic reactions or infections with
helminth parasites. Most of the cytokines associated with type 2 immune responses are IL-4 …

Thymic stromal lymphopoietin (TSLP) overexpression is widely associated with atopy.
However, TSLP is expressed in normal barrier organs, suggesting a homeostatic function …

Interleukins are considered to be potential therapeutic targets that can alter the prognosis
and disease progression of IBD. IL-21 has proven to be involved in effector Th1, Th2 and …