Cardiac arrhythmias cause significant morbidity and mortality and pose a major public
health problem. They arise from disruptions in the normally orderly propagation of cardiac …

Normal and abnormal cardiac rhythms are of key physiological and clinical interest. This
introductory article begins from Sylvio Weidmann's key historic 1950s microelectrode …

Our study was conducted to investigate whether cadherin‐5 (CDH5), a vascular endothelial
cell adhesion glycoprotein, could facilitate the differentiation of human induced pluripotent …

The synchronization of the electrical and mechanical coupling assures the physiological
pump function of the heart, but life-threatening pathologies may jeopardize this equilibrium …

Atrial fibrillation (AF), the most common arrhythmia, has been associated with different
electrophysiological, molecular, and structural alterations in atrial cardiomyocytes …

Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the
body's ever‐changing metabolic needs. This vital function is continuously regulated by the …

Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CMs) have found
utility for conducting in vitro drug screening and disease modelling to gain crucial insights …

BACKGROUND: Myocardial infarction leads to myocardial necrosis, and cardiomyocytes are
non-renewable. Fatty acid-containing cardiomyocyte maturation medium promotes …

Atrial fibrillation (AF) is the most common form of sustained arrhythmia globally, with a
prevalence of approximately 5% in individuals younger than 60 years that could triple by the …

Heterogeneity has been shown to impact resilience in a range of complex systems,
including the heart. Cardiac heterogeneity takes many forms including structural …