Primary blast injury: update on diagnosis and treatment

AE Ritenour, TW Baskin - Critical care medicine, 2008 - journals.lww.com
Background: Injuries from combat and terrorist explosions are increasing worldwide. As
such, physicians can expect to treat more patients with complex and unique patterns of …

Haemodynamic changes in trauma

E Kirkman, S Watts - British journal of anaesthesia, 2014 - academic.oup.com
Trauma is the leading cause of death during the first four decades of life in the developed
countries. Its haemodynamic response underpins the patient's initial ability to survive, and …

Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model

V Mishra, M Skotak, H Schuetz, A Heller, J Haorah… - Scientific reports, 2016 - nature.com
Injury severity in blast induced Traumatic Brain Injury (bTBI) increases with blast
overpressure (BOP) and impulse in dose-dependent manner. Pure primary blast waves …

[PDF][PDF] Blast related neurotrauma: a review of cellular injury

LY Leung, PJ VandeVord, AL Dal Cengio… - Molecular & cellular …, 2008 - cdn.techscience.cn
Historically, blast overpressure is known to affect primarily gas-containing organs such as
the lung and ear. More recent interests focus on its ability to cause damage to solid organs …

Blast injury research models

E Kirkman, S Watts, G Cooper - … Transactions of the …, 2011 - royalsocietypublishing.org
Blast injuries are an increasing problem in both military and civilian practice. Primary blast
injury to the lungs (blast lung) is found in a clinically significant proportion of casualties from …

Prolonged permissive hypotensive resuscitation is associated with poor outcome in primary blast injury with controlled hemorrhage

J Garner, S Watts, C Parry, J Bird, G Cooper… - Annals of …, 2010 - journals.lww.com
Objective: To determine the effects of primary blast injury (PBI) on survival and the
physiological response to resuscitation after hemorrhagic shock. Background: Air-blast …

Pathophysiology of primary blast injury

JE Smith, J Garner - BMJ Military Health, 2019 - militaryhealth.bmj.com
The majority of patients injured in the recent conflicts in Iraq and Afghanistan were as a
result of explosion, and terrorist incidents have brought blast injuries to the front door of …

Abdominal trauma in primary blast injury

C Owers, JL Morgan, JP Garner - Journal of British Surgery, 2011 - academic.oup.com
Background Blast injury is uncommon, and remains poorly understood by most clinicians
outside regions of active warfare. Primary blast injury (PBI) results from the interaction of the …

Preclinical models for studying immune responses to traumatic injury

JK Skelton, R Purcell - Immunology, 2021 - Wiley Online Library
Traumatic injury initiates a large and complex immune response in the minutes after the
initial insult, comprising of simultaneous pro‐and anti‐inflammatory responses. In patients …

Development of a large animal model for investigating resuscitation after blast and hemorrhage

JP Garner, S Watts, C Parry, J Bird, E Kirkman - World journal of surgery, 2009 - Springer
Background Blast injuries are an increasing problem owing to the widespread terrorist
threat, but hemorrhage remains the second leading cause of civilian trauma death. Against …