Rheumatoid arthritis (RA), a multigene disorder with a heritability rate of 60%, is
characterized by persistent pain, synovial hyperplasia, and cartilage and bone destruction …

Ethnopharmacological relevance Herba taxilli (HT, Sangjisheng in Chinese), which is
composed of the dried stems and leaves of Taxillus chinensis (DC.) Danser, has been …

Background The high prevalence of chronic inflammatory diseases or autoimmune reactions
is a major source of concern and affects the quality of life of patients. Chronic inflammatory …

Ethnopharmacological relevance The dried aboveground part of Geranium Wilfordii
Maxim.(G. Wilfordii) is a traditional Chinese herbal medicine named lao-guan-cao. It has …

Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by uncontrolled
joint inflammation and damage to bone and cartilage. Previous studies have shown that …

Rheumatoid arthritis (RA) is a chronic inflammatory disease mainly affecting the synovial
joints. A highly potent antagonist of CC chemokine receptor 5 (CCR5), maraviroc (MVC) …

Ethnopharmacological relevance Gout belongs to the category of" arthralgia syndrome" in
traditional Chinese medicine. It is believed that gout is caused by stagnation of blood stasis …

Autism is a neurodevelopmental disorder characterized by qualitative impairment in
communication, social interaction, and repetitive stereotypic behavior. Resveratrol plays a …

Several studies have suggested that chemokine receptors are important mediators of
inflammatory response in rheumatoid arthritis (RA). B cells are also known to play an …

Synovial tissue hyperplasia is a major cause of bone damage in rheumatoid arthritis (RA).
Over-proliferation and secretion of cytokines of fibroblast-like synoviocytes (FLSs) are key …