Despite advances in understanding the development and progression of cancer in recent
years, there remains a lack of comprehensive characterization of the cancer glycoproteome …

Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

Intact N-glycopeptide analysis remains challenging due to the complexity of glycopeptide
structures, low abundance of glycopeptides in protein digests, and difficulties in data …

Protein glycosylation plays a key role in various biological processes and disease-related
pathological progression. Mass spectrometry (MS)-based glycoproteomics is a powerful …

Hepatocellular carcinoma (HCC) is the third most‐common cause of cancer‐related death
worldwide. Most cases of HCC develop in patients that already have liver cirrhosis and have …

Most proteins in serum are glycosylated, with several annotated as biomarkers and thus
diagnostically important and of interest for their role in disease. Most methods for analyzing …

Recent advances in analytical techniques provide the opportunity to quantify even low‐
abundance glycopeptides derived from complex biological mixtures, allowing for the …

Protein glycosylation is one of the most common posttranslational modifications, and plays
an essential role in a wide range of biological processes such as immune response …

Glycosylation is one of the most significant and abundant post-translational modifications in
cells. Glycomic and glycoproteomic analyses involve the characterization of …

Currently, surveillance strategies have inadequate performance for cirrhosis and early
detection of hepatocellular carcinoma (HCC). The glycosylation of serum haptoglobin has …