Carbon monoxide poisoning: pathogenesis, management, and future directions of therapy

JJ Rose, L Wang, Q Xu, CF McTiernan… - American journal of …, 2017 - atsjournals.org
Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The
clinical presentation runs a spectrum, ranging from headache and dizziness to coma and …

Carbon Monoxide Poisoning: From Microbes to Therapeutics

MR Dent, JJ Rose, J Tejero… - Annual review of …, 2024 - annualreviews.org
Carbon monoxide (CO) poisoning leads to 50,000–100,000 emergency room visits and
1,500–2,000 deaths each year in the United States alone. Even with treatment, survivors …

Amifostine, a radioprotectant agent, protects rat brain tissue lipids against ionizing radiation induced damage: an FTIR microspectroscopic imaging study

G Cakmak, LM Miller, F Zorlu, F Severcan - Archives of biochemistry and …, 2012 - Elsevier
Amifostine is the only approved radioprotective agent by FDA for reducing the damaging
effects of radiation on healthy tissues. In this study, the protective effect of amifostine against …

Mechanisms and therapeutic targets of carbon monoxide poisoning: a focus on reactive oxygen species

T Wang, Y Zhang - Chemico-biological interactions, 2024 - Elsevier
Carbon monoxide (CO) poisoning presents a substantial public health challenge that
necessitates the identification of its pathological mechanisms and therapeutic targets. CO …

[HTML][HTML] Carbon Monoxide: A Pleiotropic Redox Regulator of Life and Death

AY Abramov, I Myers, PR Angelova - Antioxidants, 2024 - mdpi.com
Despite recent technological progress, carbon monoxide poisoning is still one of the leading
causes of domestic and industrial morbidity and mortality. The brain is particularly …

Combined application of dexamethasone and hyperbaric oxygen therapy yields better efficacy for patients with delayed encephalopathy after acute carbon monoxide …

W Xiang, H Xue, B Wang, Y Li, J Zhang… - Drug Design …, 2017 - Taylor & Francis
Background Delayed encephalopathy after acute carbon monoxide (CO) poisoning
(DEACMP) commonly occurs after recovering from acute CO poisoning. This study was …

Structural and functional damages of whole body ionizing radiation on rat brain homogenate membranes and protective effect of amifostine

G Cakmak, M Severcan, F Zorlu… - International journal of …, 2016 - Taylor & Francis
Purpose: To investigate the effects of whole body ionizing radiation at a sublethal dose on
rat brain homogenate membranes and the protective effects of amifostine on these systems …

After treatment with methylene blue is effective against delayed encephalopathy after acute carbon monoxide poisoning

N Zhao, P Liang, X Zhuo, C Su, X Zong… - Basic & Clinical …, 2018 - Wiley Online Library
Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) is the
most severe and clinically intractable complication that occurs following acute CO poisoning …

The efficacy of N-butylphthalide and dexamethasone combined with hyperbaric oxygen on delayed encephalopathy after acute carbon monoxide poisoning

J Zhang, Y Guo, W Li, G Li, Y Chen - Drug Design, Development …, 2020 - Taylor & Francis
Background Carbon monoxide (CO) poisoning is a common health problem among people
in many countries, primarily because of its severe clinical effects and high toxicological …

Diffusion tensor imaging for predicting the clinical outcome of delayed encephalopathy of acute carbon monoxide poisoning

X Hou, L Ma, L Wu, Y Zhang, H Ge, Z Li, Y Gao… - European …, 2013 - karger.com
Objective: The aim of the present study was to determine the relationship between
neuropsychiatric outcomes and diffusion tensor imaging (DTI) in patients with delayed …