Human alpha class glutathione S‐transferases: genetic polymorphism, expression, and susceptibility to disease
BF Coles, FF Kadlubar - Methods in enzymology, 2005 - Elsevier
The human alpha class glutathione S‐transferases (GSTs) consist of 5 genes, hGSTA1–
hGSTA5, and 7 pseudogenes on chromosome 6p12. 1–6p12. 2. hGSTA1–hGSTA4 have …
hGSTA5, and 7 pseudogenes on chromosome 6p12. 1–6p12. 2. hGSTA1–hGSTA4 have …
Autism spectrum disorders may be due to cerebral toxoplasmosis associated with chronic neuroinflammation causing persistent hypercytokinemia that resulted in an …
J Prandota - Research in Autism Spectrum Disorders, 2010 - Elsevier
Worldwide, approximately 2 billion people are chronically infected with Toxoplasma gondii
with largely yet unknown consequences. Patients with autism spectrum disorders (ASD) …
with largely yet unknown consequences. Patients with autism spectrum disorders (ASD) …
IL-4 plays a crucial role in regulating oxidative damage in the liver during schistosomiasis
AC La Flamme, EA Patton, B Bauman… - The Journal of …, 2001 - journals.aai.org
Liver enlargement and hepatocyte proliferation, normal responses in wild-type (WT) mice
infected with the parasitic helminth Schistosoma mansoni, were found to be severely …
infected with the parasitic helminth Schistosoma mansoni, were found to be severely …
Detection of immunotoxicity of benzo [a] pyrene in a subacute toxicity study after oral exposure in rats.
WH De Jong, ED Kroese, JG Vos… - … sciences: an official …, 1999 - academic.oup.com
In an extended OECD 407 study protocol, including immune parameters, male Riv: Tox
Wistar SPF rats were treated for 35 days with benzo [a] pyrene (B [a] p)(3, 10, 30, or 90 …
Wistar SPF rats were treated for 35 days with benzo [a] pyrene (B [a] p)(3, 10, 30, or 90 …
IL-4 suppresses the expression and the replication of hepatitis B virus in the hepatocellular carcinoma cell line Hep3B
SJ Lin, PY Shu, C Chang, AK Ng… - The Journal of Immunology, 2003 - journals.aai.org
IL-4 has been known as a Th2 cytokine and can act on B cells, T cells, and monocytes. In
this study we demonstrate that IL-4Rs are expressed on human hepatocellular carcinoma …
this study we demonstrate that IL-4Rs are expressed on human hepatocellular carcinoma …
Important role of proinflammatory cytokines/other endogenous substances in drug-induced hepatotoxicity: depression of drug metabolism during infections …
J Prandota - American journal of therapeutics, 2005 - journals.lww.com
Abstract Analysis of literature data on drug-induced hepatotoxicity reveals that often upper
respiratory febrile illnesses and/or inflammation states precede liver injury/diseases related …
respiratory febrile illnesses and/or inflammation states precede liver injury/diseases related …
Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450 isoforms in hepatitis of mice infected with Helicobacter hepaticus.
MA Sipowicz, P Chomarat, BA Diwan… - The American journal …, 1997 - ncbi.nlm.nih.gov
A recently discovered bacterium, Helicobacter hepaticus, infects the intrahepatic bile
canaliculi of mice, causing a severe chronic hepatitis culminating in liver cancer. Thus, it …
canaliculi of mice, causing a severe chronic hepatitis culminating in liver cancer. Thus, it …
Цитокины как регуляторы цитохром p450-зависимых монооксигеназ. теоретические и прикладные аспекты
СВ Сибиряк - Цитокины и воспаление, 2003 - elibrary.ru
Цитохром Р450-зависимые монооксигеназы обеспечивают окислительную
биотрансформацию поступающих в организм чужеродных химических соединений …
биотрансформацию поступающих в организм чужеродных химических соединений …
Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG cell-based biosensors to monitor hepatocyte differentiation, drug metabolism and toxicity
M Vlach, N Quesnot, H Dubois-Pot-Schneider… - Sensors, 2019 - mdpi.com
Human hepatoma HepaRG cells express most drug metabolizing enzymes and constitute a
pertinent in vitro alternative cell system to primary cultures of human hepatocytes in order to …
pertinent in vitro alternative cell system to primary cultures of human hepatocytes in order to …
Relative levels of IL4 and IFN-γ in complicated malaria: Association with IL4 polymorphism and peripheral parasitemia
P Tangteerawatana, S Pichyangkul, M Hayano… - Acta tropica, 2007 - Elsevier
Functional IL4-590 C/T polymorphisms and the relative amounts of IL4 and IFN-γ were
investigated in relation to severity of malaria in 110 and 169 Thai patients with complicated …
investigated in relation to severity of malaria in 110 and 169 Thai patients with complicated …