Leishmania exosomes and other virulence factors: Impact on innate immune response and macrophage functions

VD Atayde, K Hassani, A da Silva Lira Filho… - Cellular …, 2016 - Elsevier
Leishmania parasites are the causative agents of the leishmaniases, a collection of vector-
borne diseases that range from simple cutaneous to fatal visceral forms. Employing potent …

Cardiovascular risk in adult patients with growth hormone (GH) deficiency and following substitution with GH—an update

C Gazzaruso, M Gola, I Karamouzis… - The Journal of …, 2014 - academic.oup.com
Context: GH deficiency (GHD) of the adult is a clinical condition characterized by the
presence of several traditional and emerging cardiovascular risk factors that can significantly …

Association of irisin with fat mass, resting energy expenditure, and daily activity in conditions of extreme body mass index

M Pardo, AB Crujeiras, M Amil, Z Aguera… - International journal …, 2014 - Wiley Online Library
FNDC5/irisin has been recently postulated as beneficial in the treatment of obesity and
diabetes because it is induced in muscle by exercise, increasing energy expenditure …

LncRNA-mediated adipogenesis in different adipocytes

P Zhang, S Wu, Y He, X Li, Y Zhu, X Lin… - International Journal of …, 2022 - mdpi.com
Long-chain noncoding RNAs (lncRNAs) are RNAs that do not code for proteins, widely
present in eukaryotes. They regulate gene expression at multiple levels through different …

Chemerin: a potential endocrine link between obesity and type 2 diabetes

AA Roman, SD Parlee, CJ Sinal - Endocrine, 2012 - Springer
Obesity and type 2 diabetes have reached epidemic levels and account for a substantial
portion of the annual health expenditures of developed nations. While there is an …

Omics biomarkers in obesity: novel etiological insights and targets for precision prevention

K Aleksandrova, C Egea Rodrigues, A Floegel… - Current obesity …, 2020 - Springer
Abstract Purpose of Review Omics-based technologies were suggested to provide an
advanced understanding of obesity etiology and its metabolic consequences. This review …

Role of chemerin in cardiovascular diseases

MT Macvanin, M Rizzo, J Radovanovic, A Sonmez… - Biomedicines, 2022 - mdpi.com
(1) Background: Obesity is closely connected to the pathophysiology of cardiovascular
diseases (CVDs). Excess fat accumulation is associated with metabolic malfunctions that …

Subfatin is a novel adipokine and unlike Meteorin in adipose and brain expression

ZY Li, SL Zheng, P Wang, TY Xu… - CNS neuroscience & …, 2014 - Wiley Online Library
Aims Adipose tissue releases adipokines that play important roles in metabolic and cardio‐
cerebro‐vascular homeostasis. This study was to discover novel adipokines using caloric …

Mechanisms by which obesity regulates inflammation and anti-tumor immunity in cancer.

CE Maracle, CL McCallister, RD Egelton… - Biochemical and …, 2024 - Elsevier
Obesity is associated with an increased risk for 13 different cancers. The increased risk for
cancer in obesity is mediated by obesity-associated changes in the immune system. Obesity …

Power of metabolomics in biomarker discovery and mining mechanisms of obesity

A Zhang, H Sun, X Wang - Obesity Reviews, 2013 - Wiley Online Library
Obesity, the prevalence of which is increasing rapidly worldwide, is recognized as a risk
factor for diabetes, cardiovascular disease, liver disease and renal disease. Unfortunately …