The COVID-19 pandemic

M Ciotti, M Ciccozzi, A Terrinoni, WC Jiang… - Critical reviews in …, 2020 - Taylor & Francis
In December 2019, an outbreak of pneumonia of unknown origin was reported in Wuhan,
Hubei Province, China. Pneumonia cases were epidemiologically linked to the Huanan …

[HTML][HTML] COVID-19 vaccine development and a potential nanomaterial path forward

MD Shin, S Shukla, YH Chung, V Beiss… - Nature …, 2020 - nature.com
The COVID-19 pandemic has infected millions of people with no clear signs of abatement
owing to the high prevalence, long incubation period and lack of established treatments or …

[PDF][PDF] Perspectives on monoclonal antibody therapy as potential therapeutic intervention for Coronavirus disease-19 (COVID-19)

B Shanmugaraj, K Siriwattananon… - Asian Pacific journal …, 2020 - apjai-journal.org
Last decade witnessed the outbreak of many life-threatening human pathogens including
Nipah, Ebola, Chikungunya, Zika, Middle East respiratory syndrome coronavirus (MERS …

Remdesivir against COVID-19 and other viral diseases

JJ Malin, I Suárez, V Priesner… - Clinical microbiology …, 2020 - Am Soc Microbiol
Patients and physicians worldwide are facing tremendous health care hazards that are
caused by the ongoing severe acute respiratory distress syndrome coronavirus 2 (SARS …

[HTML][HTML] Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

[HTML][HTML] A randomized, controlled trial of Ebola virus disease therapeutics

S Mulangu, LE Dodd, RT Davey Jr… - New England journal …, 2019 - Mass Medical Soc
Background Although several experimental therapeutics for Ebola virus disease (EVD) have
been developed, the safety and efficacy of the most promising therapies need to be …

[HTML][HTML] Mechanism of inhibition of Ebola virus RNA-dependent RNA polymerase by remdesivir

EP Tchesnokov, JY Feng, DP Porter, M Götte - Viruses, 2019 - mdpi.com
Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug
that shows broad-spectrum antiviral activity against several RNA viruses. This compound is …

[HTML][HTML] Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China

RL Kruse - F1000Research, 2020 - ncbi.nlm.nih.gov
Abstract A novel coronavirus (2019-nCoV) originating in Wuhan, China presents a potential
respiratory viral pandemic to the world population. Current efforts are focused on …

Treating COVID-19—off-label drug use, compassionate use, and randomized clinical trials during pandemics

AC Kalil - Jama, 2020 - jamanetwork.com
In the 2014 Ebola outbreak, close to 30 000 individuals developed Ebola viral disease
(EVD), and numerous therapies were tested against this virus, including chloroquine …