Diabetes mellitus is one of the most challenging threats to global public health. To improve
the therapy efficacy of antidiabetic drugs, numerous drug delivery systems have been …

Lipotoxicity is a fundamental pathophysiologic mechanism in diabetes and non-alcoholic
fatty liver disease and is now increasingly recognized in diabetic kidney disease (DKD) …

Excessive expansion of adipocytes can have unhealthy consequences as excess free fatty
acids enter other tissues and cause ectopic fat deposition by resynthesizing triglycerides …

Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is the most
significant microvascular complication of diabetes and poses a severe public health concern …

Lipotoxicity is the dysregulation of the lipid environment and/or intracellular composition that
leads to accumulation of harmful lipids and ultimately to organelle dysfunction, abnormal …

The global prevalence of diabetes mellitus (DM) has led to widespread multi-system
damage, especially in cardiovascular and renal functions, heightening morbidity and …

In this study, we aimed to isolate and identify the bioactive compounds from 5-year pickled
radish. The pickled radish was extracted with methanol or ethyl acetate. Sephadex LH-20 …

Diabetic nephropathy (DN) involves serious lipid metabolism disorder, and renal ectopic
lipid deposition aggravates DN progression. However, the molecular mechanism of renal …

Oxidative stress, a hallmark pathophysiological feature in diabetic kidney disease (DKD),
arises from the intricate interplay between pro-oxidants and anti-oxidants. While …

Liraglutide is a glucagon-like peptide-1 receptor agonist used as a treatment for type 2
diabetes mellitus, which has been expanded for use at a higher dose in weight control …