Metabolism of polyamines and kidney disease: a promising therapeutic target

D Luo, X Lu, Y Li, Y Xu, Y Zhou, H Mao - Kidney Diseases, 2023 - karger.com
Background: More than 850 million people worldwide suffer from acute and chronic kidney
diseases (CKD) which are tremendous socioeconomic burdens for society. Currently, the …

[HTML][HTML] Polyamines: Key Players in Immunometabolism and Immune Regulation

SS Mahalingam, P Pandiyan - Journal of cellular immunology, 2024 - pmc.ncbi.nlm.nih.gov
Polyamines are small organic molecules ubiquitously present in all living organisms and
function as crucial regulators of biological processes ranging from fundamental cellular …

Polyamines and hypusination are important for Clostridioides difficile toxin B (TcdB)-mediated activation of group 3 innate lymphocytes (ILC3s)

P Sah, BA Knighten, MA Reidy… - Infection and …, 2023 - Am Soc Microbiol
Clostridioides difficile is the most common cause of nosocomial gastrointestinal tract
bacterial infections. We lack fully effective reliable treatments for this pathogen, and there is …