Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is ubiquitously expressed in most eukaryotic
cells and functions to induce a broad range of cellular defenses against exogenous and …

Aging constitutes the main risk factor for the development of neurodegenerative diseases.
This represents a major health issue worldwide that is only expected to escalate due to the …

Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …

Neurodegenerative diseases are severely debilitating conditions characterized primarily by
progressive neuronal loss and impairment of the nervous system. Alzheimer's and …

Medicinal plants are well-known in affording clinically useful agents, with rich medicinal
values by combining with disease targets through various mechanisms. Plant secondary …

Background Regenerative therapies to mitigate Alzheimer's disease (AD) neuropathology
have shown very limited success. In the recent era, extracellular vesicles (EVs) derived from …

Abstract Parkinson's disease (PD), characterized by loss of nigrostriatal dopaminergic
neurons, is one of the most predominant neurodegenerative diseases affecting the elderly …

Currently there are no therapies for treating Alzheimer's disease (AD) that can effectively halt
disease progression. Existing drugs such as acetylcholinesterase inhibitors or NMDA …