Early adversity and development: parsing heterogeneity and identifying pathways of risk and resilience

DG Gee - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Adversity early in life is common and is a major risk factor for the onset of psychopathology.
Delineating the neurodevelopmental pathways by which early adversity affects mental …

Cannabis and the developing brain: insights into its long-lasting effects

YL Hurd, OJ Manzoni, MV Pletnikov, FS Lee… - Journal of …, 2019 - Soc Neuroscience
The recent shift in sociopolitical debates and growing liberalization of cannabis use across
the globe has raised concern regarding its impact on vulnerable populations, such as …

Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure

EM Cohodes, ER Kitt… - Developmental …, 2021 - Wiley Online Library
Early‐life stress confers profound and lasting risk for developing cognitive, social, emotional,
and physical health problems. The effects of stress on the developing brain contribute to this …

Adolescent decision making: A decade in review

G Icenogle, E Cauffman - Journal of research on adolescence, 2021 - Wiley Online Library
Research in the past decade has highlighted the nuances of adolescent decision making. In
this review article, we summarize several themes evident in the field of developmental …

Translating developmental neuroscience to understand risk for psychiatric disorders

HC Meyer, FS Lee - American Journal of Psychiatry, 2019 - Am Psychiatric Assoc
The transition from childhood to adulthood represents the developmental time frame in
which the majority of psychiatric disorders emerge. Recent efforts to identify risk factors …

Learning about safety: Conditioned inhibition as a novel approach to fear reduction targeting the developing brain

P Odriozola, DG Gee - American journal of psychiatry, 2021 - Am Psychiatric Assoc
Adolescence is a peak time for the onset of psychiatric disorders, with anxiety disorders
being the most common and affecting as many as 30% of youths. A core feature of anxiety …

Signatures of sex: Sex differences in gene expression in the vertebrate brain

B Gegenhuber, J Tollkuhn - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Women and men differ in disease prevalence, symptoms, and progression rates for many
psychiatric and neurological disorders. As more preclinical studies include both sexes in …

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

T Santos-Silva, D Hazar Ülgen, CFB Lopes… - Translational …, 2023 - nature.com
Adolescent individuals exhibit great variability in cortical dynamics and behavioral
outcomes. The developing adolescent brain is highly sensitive to social experiences and …

Characterizing experiential elements of early-life stress to inform resilience: Buffering effects of controllability and predictability and the importance of their timing

EM Cohodes, LM Sisk, TJ Keding… - Development and …, 2023 - cambridge.org
Key theoretical frameworks have proposed that examining the impact of exposure to specific
dimensions of stress at specific developmental periods is likely to yield important insight into …

Development and validation of the Dimensional Inventory of Stress and Trauma Across the Lifespan (DISTAL): A novel assessment tool to facilitate the dimensional …

EM Cohodes, S McCauley, JC Pierre… - Developmental …, 2023 - Wiley Online Library
Decades of research underscore the profound impact of adversity on brain and behavioral
development. Recent theoretical models have highlighted the importance of considering …