The cholinergic system in the pathophysiology and treatment of Alzheimer's disease
Cholinergic synapses are ubiquitous in the human central nervous system. Their high
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier
DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …
Gut microbiome alterations in Alzheimer's disease
NM Vogt, RL Kerby, KA Dill-McFarland, SJ Harding… - Scientific reports, 2017 - nature.com
Alzheimer's disease (AD) is the most common form of dementia. However, the
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …
Therapeutic potential of vital transcription factors in Alzheimer's and Parkinson's disease with particular emphasis on transcription factor EB mediated autophagy
Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …
Current and future treatments for Alzheimer's disease
KG Yiannopoulou… - Therapeutic advances in …, 2013 - journals.sagepub.com
Alzheimer's dementia (AD) is increasingly being recognized as one of the most important
medical and social problems in older people in industrialized and non-industrialized …
medical and social problems in older people in industrialized and non-industrialized …
Bioinorganic chemistry of Alzheimer's disease
KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Neurodegenerative diseases: Regenerative mechanisms and novel therapeutic approaches
Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …
Effects of virtual reality intervention on cognition and motor function in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis
S Zhu, Y Sui, Y Shen, Y Zhu, N Ali, C Guo… - Frontiers in aging …, 2021 - frontiersin.org
Background: Virtual reality (VR) intervention is an innovative and efficient rehabilitative tool
for patients affected by stroke, Parkinson's disease, and other neurological disorders. This …
for patients affected by stroke, Parkinson's disease, and other neurological disorders. This …
An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease
A Haake, K Nguyen, L Friedman… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is the most common cause of major neurocognitive
disorders with a prevalence in the US of about 5.7 million in 2018. With the disease burden …
disorders with a prevalence in the US of about 5.7 million in 2018. With the disease burden …
New approaches for the treatment of Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent chronic neurodegenerative disease. Current
approved therapies are symptomatic treatments having some effect on cognitive function …
approved therapies are symptomatic treatments having some effect on cognitive function …