The P2X7 receptor (P2X7R) is a nonselective cation channel that is activated by
extracellular ATP and triggers the secretion of several proinflammatory substances, such as …

Cancer pain is the most prevalent symptom experienced by cancer patients. It substantially
impacts a patient's long-term physical and emotional health, making it a pressing issue that …

ATP is an important regulator of microglia and its effects on microglial cytokine release are
currently discussed as important contributors in a variety of brain diseases. We here …

Mitogen-activated protein (MAP) kinase signaling cascades play important roles in
eukaryotic defense against various pathogens. Activation of the extracellular ATP (eATP) …

Over the past decades, evidences have consistently shown that Neuroinflammation is a
critical underlying process in a range of CNS diseases, including neurodegenerative …

Are the symptoms of autism caused by a treatable metabolic syndrome that traces to the
abnormal persistence of a normal, alternative functional state of mitochondria? A small …

Abstract Fifty-one 1, 2, 3-triazole derivatives were synthesized and evaluated with respect to
P2X7 receptor (P2X7R) activity and its associated pore. These triazoles were screened in …

Salt stress releases extracellular ATP to activate purinergic signaling and inhibit plant growth |
Plant Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Nonalcoholic fatty liver disease (NAFLD) is considered a manifestation of metabolic
syndrome (MS) and is characterized by the accumulation of triglycerides and a varying …

Enhancers are transcriptional regulatory elements that increase target gene expression. It
has reported that enhancers could universally transcribe into enhancer RNAs (eRNAs) with …