Intracellular redox-modulated pathways as targets for effective approaches in the treatment of viral infection
Host-directed therapy using drugs that target cellular pathways required for virus lifecycle or
its clearance might represent an effective approach for treating infectious diseases …
its clearance might represent an effective approach for treating infectious diseases …
Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration
M Saberi, X Zhang, A Mobasheri - Geroscience, 2021 - Springer
The prevalence of rheumatic and musculoskeletal diseases (RMDs) including osteoarthritis
(OA) and low back pain (LBP) in aging societies present significant cost burdens to health …
(OA) and low back pain (LBP) in aging societies present significant cost burdens to health …
PTEN inhibition attenuates endothelial cell apoptosis in coronary heart disease via modulating the AMPK–CREB–Mfn2‐mitophagy signaling pathway
P Li, J Wang, X Zhao, J Ru, T Tian, Y An… - Journal of Cellular …, 2020 - Wiley Online Library
Atherosclerosis (AS) is a major pathogenic factor in patients with cardiovascular diseases,
and endothelial dysfunction (ED) plays a primary role in the occurrence and development of …
and endothelial dysfunction (ED) plays a primary role in the occurrence and development of …
[HTML][HTML] N-Acetyl Cysteine Overdose Induced Acute Toxicity and Hepatic Microvesicular Steatosis by Disrupting GSH and Interfering Lipid Metabolisms in Normal Mice
MS Tsai, GG Liou, JW Liao, PY Lai, DJ Yang, SH Wu… - Antioxidants, 2024 - mdpi.com
N-acetyl cysteine (NAC) is a versatile drug used in various conditions, but the limitations and
toxicities are not clear. The acute toxicity and toxicological mechanisms of an intraperitoneal …
toxicities are not clear. The acute toxicity and toxicological mechanisms of an intraperitoneal …
N-acetylcysteine and coronavirus disease 2019: May it work as a beneficial preventive and adjuvant therapy? A comprehensive review study
Background: Coronaviruses are major pathogens of respiratory system causing different
disorders, including the common cold, Middle East respiratory syndrome, and severe acute …
disorders, including the common cold, Middle East respiratory syndrome, and severe acute …
Antitumor activities for two Pt (II) complexes of tropolone and 8-hydroxyquinoline derivative
X Mo, K Chen, Z Chen, B Chu, D Liu, Y Liang… - Inorganic …, 2021 - ACS Publications
The reactions of cis-Pt (DMSO) 2Cl2 and tropolone (HL) with 8-hydroxyquinoline (HQ) or 2-
methyl-8-hydroxyquinoline (HMQ) gave [Pt (Q)(L)](1) and [Pt (MQ)(L)](2), which present …
methyl-8-hydroxyquinoline (HMQ) gave [Pt (Q)(L)](1) and [Pt (MQ)(L)](2), which present …
Exploring the Antiproliferative and Modulatory Effects of 1-Methoxyisobrassinin on Ovarian Cancer Cells: Insights into Cell Cycle Regulation, Apoptosis, Autophagy …
M Zigová, V Miškufová, M Budovská, R Michalková… - Molecules, 2024 - mdpi.com
Ovarian cancer, a highly lethal malignancy among reproductive organ cancers, poses a
significant challenge with its high mortality rate, particularly in advanced-stage cases …
significant challenge with its high mortality rate, particularly in advanced-stage cases …
Therapeutic effect of N-acetyl cysteine as an antioxidant on rainbow trout's brain in cypermethrin toxicity
The aim of this study was to investigate the therapeutic effect of N-acetylcystein (NAC)
against oxidative stress induced by Cypermethrin pesticide in rainbow trout (Oncorhynchus …
against oxidative stress induced by Cypermethrin pesticide in rainbow trout (Oncorhynchus …
[HTML][HTML] N-Acetylcysteine Mitigates Oxidative Stress Induced by Transplanting Lettuce Seedlings into a DFT Hydroponic System
M Sakamoto, T Suzuki - Agronomy, 2024 - mdpi.com
Oxidative stress results from an imbalance between the production and accumulation of
reactive oxygen species (ROS), which can impede plant growth under various …
reactive oxygen species (ROS), which can impede plant growth under various …
Role of Klotho and N-acetylcysteine in oxidative stress associated with the vitrification of ovarian tissue cytoprotective function of Klotho in cryopreservation
B Kim, SM Lee, SJ Park, S Lee, T Kim - Tissue Engineering and …, 2023 - Springer
Background: Cryopreservation can cause mechanical and chemical stress, ultimately
leading to the formation of reactive oxygen species (ROS) and oxidative stress. ROS inhibits …
leading to the formation of reactive oxygen species (ROS) and oxidative stress. ROS inhibits …