Alzheimer's disease: a review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

P dos Santos, C Leide, PF Ozela… - Current medicinal …, 2018 - ingentaconnect.com
Dementia is characterized by the impairment of cognition and behavior of people over 65
years. Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the …

Smoking and increased Alzheimer's disease risk: a review of potential mechanisms

TC Durazzo, N Mattsson, MW Weiner… - Alzheimer's & …, 2014 - Wiley Online Library
Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

Plasma phospholipids identify antecedent memory impairment in older adults

M Mapstone, AK Cheema, MS Fiandaca, X Zhong… - Nature medicine, 2014 - nature.com
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …

Military traumatic brain injury: a review

JC Chapman, R Diaz‐Arrastia - Alzheimer's & Dementia, 2014 - Wiley Online Library
Military mild traumatic brain injury (mTBI) differs from civilian injury in important ways.
Although mTBI sustained in both military and civilian settings are likely to be underreported …

The critical need for defining preclinical biomarkers in Alzheimer's disease

MS Fiandaca, ME Mapstone, AK Cheema… - Alzheimer's & …, 2014 - Wiley Online Library
The increasing number of afflicted individuals with late‐onset Alzheimer's disease (AD)
poses significant emotional and financial burden on the world's population. Therapeutics …

Maladaptive autonomic regulation in PTSD accelerates physiological aging

JB Williamson, EC Porges, DG Lamb… - Frontiers in …, 2015 - frontiersin.org
A core manifestation of post-traumatic stress disorder (PTSD) is a disconnection between
physiological state and psychological or behavioral processes necessary to adequately …

Dementia in military and veteran populations: a review of risk factors—traumatic brain injury, post-traumatic stress disorder, deployment, and sleep

Z Raza, SF Hussain, S Ftouni, G Spitz, N Caplin… - Military medical …, 2021 - Springer
The military population face a unique set of risk factors that may increase the risk of being
diagnosed with dementia. Traumatic brain injury (TBI) and post-traumatic stress disorder …

The disease intersection of susceptibility and exposure: chemical exposures and neurodegenerative disease risk

CM Tanner, SM Goldman, GW Ross… - Alzheimer's & …, 2014 - Wiley Online Library
Alzheimer's disease, Parkinson's disease, and motor neuron disease, the most common of
the late‐life neurodegenerative disorders, are in most cases thought to have complex …

Subjective cognitive concerns, APOE ε4, PTSD symptoms, and risk for dementia among older veterans

ZE Neale, JR Fonda, MW Miller, EJ Wolf… - Alzheimer's research & …, 2024 - Springer
Background Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are
associated with self-reported problems with cognition as well as risk for Alzheimer's disease …

Cognitive changes and dementia risk after traumatic brain injury: implications for aging military personnel

AS Vincent, TM Roebuck‐Spencer… - Alzheimer's & …, 2014 - Wiley Online Library
Traumatic brain injury (TBI) is recognized as an important risk factor for the long‐term
cognitive health of military personnel, particularly in light of growing evidence that TBI …