Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease

V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease

A Li, M Gao, B Liu, Y Qin, L Chen, H Liu, H Wu… - Cell death & …, 2022 - nature.com
Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Biomedical applications of carbon nanomaterials: fullerenes, quantum dots, nanotubes, nanofibers, and graphene

M Gaur, C Misra, AB Yadav, S Swaroop… - Materials, 2021 - mdpi.com
Carbon nanomaterials (CNMs) have received tremendous interest in the area of
nanotechnology due to their unique properties and flexible dimensional structure. CNMs …

Skin barrier immunity and ageing

ES Chambers, M Vukmanovic‐Stejic - Immunology, 2020 - Wiley Online Library
The skin is the outermost layer of the body with an extensive surface area of approximately
1· 8 m2, and is the first line of defence against a multitude of external pathogens and …

Mitochondrial dysfunction and therapeutic perspectives in cardiovascular diseases

Y Liu, Y Huang, C Xu, P An, Y Luo, L Jiao… - International journal of …, 2022 - mdpi.com
High mortality rates due to cardiovascular diseases (CVDs) have attracted worldwide
attention. It has been reported that mitochondrial dysfunction is one of the most important …

NLRP3 inflammasome activation controls vascular smooth muscle cells phenotypic switch in atherosclerosis

F Burger, D Baptista, A Roth, RF da Silva… - International Journal of …, 2021 - mdpi.com
(1) Background: Monocytes and nucleotide-binding oligomerization domain-like receptor
protein 3 (NLRP3) inflammasome orchestrate lipid-driven amplification of vascular …

The Antioxidant Effect of Small Extracellular Vesicles Derived from Aloe vera Peels for Wound Healing

MK Kim, YC Choi, SH Cho, JS Choi… - Tissue engineering and …, 2021 - Springer
Abstract Background: Extracellular vesicles (EVs) derived from plants have emerged as
potential candidates for cosmetic and therapeutic applications. In this study, we isolated EVs …

Mitochondrial dysfunction in atherosclerosis

W Peng, G Cai, Y Xia, J Chen, P Wu, Z Wang… - DNA and cell …, 2019 - liebertpub.com
Mitochondria are highly dynamic organelles beyond powerhouses of a cell. These
components also play important roles in cell homeostasis by regulating cell function and …

[HTML][HTML] Olive leaf extract attenuates inflammatory activation and DNA damage in human arterial endothelial cells

B Burja, T Kuret, T Janko, D Topalović… - Frontiers in …, 2019 - frontiersin.org
Olive leaf extract (OLE) is used in traditional medicine as a food supplement and as an over-
the-counter drug for a variety of its effects, including anti-inflammatory and anti …

Targeting DNA damage response in cardiovascular diseases: from pathophysiology to therapeutic implications

L Wu, JR Sowers, Y Zhang, J Ren - Cardiovascular research, 2023 - academic.oup.com
Cardiovascular diseases (CVDs) arise from a complex interplay among genomic, proteomic,
and metabolomic abnormalities. Emerging evidence has recently consolidated the presence …