Copper complexes as anticancer agents targeting topoisomerases I and II

C Molinaro, A Martoriati, L Pelinski, K Cailliau - Cancers, 2020 - mdpi.com
Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …

[PDF][PDF] A short review on chemistry of schiff base metal complexes and their catalytic application

SA Dalia, F Afsan, MS Hossain, MN Khan… - Int. J. Chem …, 2018 - researchgate.net
Schiff bases and their complexes are flexible compounds synthesized from the
condensation of an amino compound with carbonyl compounds and extensively used for …

Molecular docking, PASS analysis, bioactivity score prediction, synthesis, characterization and biological activity evaluation of a functionalized 2-butanone …

T Khan, S Dixit, R Ahmad, S Raza, I Azad… - Journal of chemical …, 2017 - Springer
Butanone thiosemicarbazone ligand was prepared by condensation reaction between
thiosemicarbazide and butanone. The ligand was characterized by 1 H NMR, 13 C NMR, FT …

Computer-aided drug design and virtual screening of targeted combinatorial libraries of mixed-ligand transition metal complexes of 2-butanone thiosemicarbazone

T Khan, R Ahmad, I Azad, S Raza, S Joshi… - … biology and chemistry, 2018 - Elsevier
The present paper deals with in silico evaluation of 32 virtually designed transition metal
complexes of 2-butanone thiosemicarbazone and N, S, O containing donor hetero-ligands …

Synthesis, biological activity, and the effect of ionization radiation on the spectral, XRD, and TGA analysis of Cu (I), Cu (II), Zn (II), and Cd (II) complexes

SA Aly, SS Hassan, HA El-Boraey… - Arabian Journal for …, 2024 - Springer
New complexes of molecular formulae of [Cu (H2L1) I](B1),[Cu (H2L) 2 (ClO4) 2](B2),[Zn
(H2L) 2 (H2O)] SO4 (B3) and [Cd (H2L) Cl] Cl (B4) of ligand N-phenyl-2-(p-tolylglycyl) …

Synthesis, spectroscopic characterization, thermal studies, and molecular docking of novel Cr (III), Fe (III), and Co (II) complexes based on Schiff base: In vitro …

SA Aly, A Eldourghamy, BA El-Fiky… - Journal of Applied …, 2023 - japsonline.com
New chelates complexes of general formulae [Cr (H2L) 2Cl3. EtOH],[Fe (H2L)(OH) SO4
(H2O). 2H2O],[Fe (HL) 2 (OH)]. H2O, and [Co (H2L)(HL) 2.1/2 EtOH] were prepared and …

Synthesis, characterization, cytotoxicity study, interaction with DNA and topoisomerase IIα of square-planar complexes with thiosemicarbazones

LTP Silva, GBS Pereira, GP de Oliveira, MA Lima… - Polyhedron, 2024 - Elsevier
In this study, we report the synthesis and characterization of eight new palladium complexes
and a nickel complex containing thiosemicarbazone ligands derived from chalcones and …

Novel QSPR modeling of stability constants of metal-thiosemicarbazone complexes by hybrid multivariate technique: GA-MLR, GA-SVR and GA-ANN

NM Quang, TX Mau, NTA Nhung, TNM An… - Journal of Molecular …, 2019 - Elsevier
The quantitative structural property relationship (QSPR) models of the logβ 11 stability
constants of M: L complexes of the structurally diverse thiosemicarbazones and several …

Developing a binuclear multi-target Bi (III) complex by optimizing 2-acetyl-3-ethylpyrazine thiosemicarbazides

MH Khan, M Cai, S Li, Z Zhang, J Zhang, X Wen… - European Journal of …, 2019 - Elsevier
On the one hand, the multi-target agents have been promising for overcoming the deficiency
of the single targeted anticancer metal agents, on the other hand, bismuth (Bi) complexes …

[HTML][HTML] Synthesis, characterization, computational studies and biological activity evaluation of Cu, Fe, Co and Zn complexes with 2-butanone thiosemicarbazone and …

T Khan, I Azad, R Ahmad, S Raza, S Dixit, S Joshi… - Excli Journal, 2018 - ncbi.nlm.nih.gov
Abstract Mixed-ligand metal (II)(M= Cu, Fe, Co and Zn) complexes containing 2-butanone
thiosemicarbazone and 1, 10-phenanthroline have been synthesized and characterized by …