Evidence derived from laboratory medicine plays a pivotal role in the diagnosis, treatment
monitoring, and prognosis of various diseases. Reference intervals (RIs) are indispensable …

Objectives Glial fibrillary acidic protein (GFAP) is a promising biomarker that could
potentially contribute to diagnosis and prognosis in neurological diseases. The biomarker is …

Introduction In this study, we aimed to create reference intervals (RI) using a large Canadian
population-based cohort, for plasma protein biomarkers with potential utility to screen …

Objectives Blood biomarkers have the potential to transform diagnosis and prognosis for
multiple neurological indications. Establishing normative data is a critical benchmark in the …

Increasing wildfire activity in forests worldwide has driven urgency in understanding current
and future fire regimes. Spatial patterns of area burned at high severity strongly shape forest …

Climate change affects marine organisms, causing migrations, biomass reduction and
extinctions,. However, the abilities of marine species to adapt to these changes remain …

Objectives Glial fibrillary acidic protein (GFAP) in blood is an emerging biomarker of brain
injury and neurological disease. Its clinical use in children is limited by the lack of a …

Immunological aging type definition requires establishing reference intervals from the
distribution of immunosenescence biomarkers conditional on age. For 1605 individuals (18 …

Testosterone (T), sex hormone binding globulin (SHBG), free testosterone (FT) and
bioavailable testosterone (BAT) are commonly employed tests in pediatric endocrinology …

Elevated levels of neurofilament light chain (NfL) in the blood is an unspecific biomarker for
damage to neuronal axons. The measurement of NfL levels in the blood can provide useful …