Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and
entrain each other, and thus affect host health and immune-mediated diseases. Here, we …

The intestine constantly encounters and adapts to the external environment shaped by
diverse dietary nutrients. However, whether and how gut adaptability to dietary challenges is …

Regenerating family member gamma, Reg3γ (the mouse homolog of human REG3A),
belonging to the antimicrobial peptides (AMPs), functions as a part of the host immune …

Background: Dietary fat intake is associated with an increased risk of colitis associated
cancer (CAC). A high-fat diet (HFD) leads to systemic low-grade inflammation. The colon is …

Physiologically, the intestinal barrier plays a crucial role in homeostasis and nutrient
absorption and prevents pathogenic entry, harmful metabolites, and endotoxin absorption …

The microbial community colonizing the gastrointestinal tract, collectively termed the gut
microbiota, is an important element of the host organism due to its impact on multiple …

Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by inflammatory
activity with distinct rhythmic fluctuations. However, the precise mechanisms governing …

Background Circadian rhythms, observed across all domains of life, enable organisms to
anticipate and prepare for diel changes in environmental conditions. In bacteria, a circadian …

Tryptophan metabolism has shown to involve in pathogenesis of various metabolic
diseases. Gut microbiota-orientated diets hold great potentials to improve metabolic health …