Abstract Purpose of Review This review describes studies that assessed the acute and
chronic effects of commonly consumed drugs on executive function, with a focus on …

The use of non-human primates (NHPs) in studies of volitional, oral self-administration of
alcohol can help address the complex interplay between stress and excessive alcohol …

Compulsive alcohol drinking, where intake persists regardless of adverse consequences,
plays a major role in the substantial costs of alcohol use disorder. However, the processes …

The dorsal striatum (DS) is implicated in behavioral and neural processes including action
control and reinforcement. Alcohol alters these processes in rodents, and it is believed that …

The underlying genetic and epigenetic mechanisms driving functional adaptations in
neuronal excitability and excessive alcohol intake are poorly understood. Small …

A major barrier to remission from an alcohol use disorder (AUD) is the continued risk of
relapse during abstinence. Assessing the neuroadaptations after chronic alcohol and …

Preclinical research over the past several decades has demonstrated a role for the γ-
aminobutyric acidB (GABAB) receptor in alcohol use disorder (AUD). This chapter offers an …

Chronic alcohol abuse is frequently considered a habitual or inflexible behavior; however,
measures of pre-existing cognitive flexibility prior to initiation of alcohol use are usually not …

Cognitive impairments, uncontrolled drinking, and neuropathological cortical changes
characterize alcohol use disorder. Dysfunction of the orbitofrontal cortex (OFC), a critical …

One in 12 adults suffer with alcohol use disorder (AUD). Studies suggest the younger the
age in which alcohol consumption begins the higher the probability of being diagnosed with …