Human and pig pluripotent stem cells: From cellular products to organogenesis and beyond

Y Xuan, B Petersen, P Liu - Cells, 2023 - mdpi.com
Pluripotent stem cells (PSCs) are important for studying development and hold great
promise in regenerative medicine due to their ability to differentiate into various cell types. In …

Charting the path: navigating embryonic development to potentially safeguard against congenital heart defects

J Bragança, R Pinto, B Silva, N Marques… - Journal of Personalized …, 2023 - mdpi.com
Congenital heart diseases (CHDs) are structural or functional defects present at birth due to
improper heart development. Current therapeutic approaches to treating severe CHDs are …

Towards human organ generation using interspecies blastocyst complementation: Challenges and perspectives for therapy

H Sarmah, A Sawada, Y Hwang, A Miura… - Frontiers in Cell and …, 2023 - frontiersin.org
Millions of people suffer from end-stage refractory diseases. The ideal treatment option for
terminally ill patients is organ transplantation. However, donor organs are in absolute …