The treatment of hepatitis C has dramatically improved over the past decade. Unlike any
other chronic viral infection, a significant proportion of patients with chronic hepatitis C can …

The aim of our study was to conduct a systematic review of studies evaluating antiviral
therapy with pegylated interferon (PEG-IFN) alfa in combination with ribavirin for the …

Liver transplantation is a life-saving therapy to correct liver failure, portal hypertension and
hepatocellular carcinoma arising from hepatitis C infection. But despite the successful use of …

Background & Aims: Recurrence of hepatitis C virus (HCV) infection is a relevant problem of
liver transplantation programs. We evaluated the effect of antiviral therapy on disease …

Pegylated interferon (pegIFN) and ribavirin eradicates hepatitis C virus (HCV) in one third of
liver recipients with recurrent disease. Side effects are frequent and potentially life …

Liver fibrosis results from an excessive wound healing response in most chronic liver
diseases, such as hepatitis C. Despite great advances in antiviral therapy in recent years …

There is currently no effective treatment for recurrent hepatitis C after orthotopic liver
transplantation (OLT). We therefore performed two randomized, controlled trials—a …

Recurrence of hepatitis C virus (HCV) infection after liver transplantation (LT) is universal.
However, the efficacy, tolerability and safety of combination interferon and ribavirin (IFN …

BACKGROUND/AIMS: HCV infection recurs almost in all HCV-positive patients receiving
liver transplantation and carries a poor prognosis. Aim of this study was to analyze efficacy …

Natural killer (NK) cells constitute the first line of host defense against invading pathogens.
They usually become activated in an early phase of a viral infection. Liver is particularly …