The key processes in biological and chemical systems are described by networks of
chemical reactions. From molecular biology to biotechnology applications, computational …

One of the main objectives of synthetic biology is the development of molecular controllers
that can manipulate the dynamics of a given biochemical network that is at most partially …

Proper functioning of any cell depends on gene regulation. Lac operon plays a major role in
regulating the cell metabolism in bacterial genes. The lac genetic switch exhibits significant …

Gene expression is regulated by a complex transcriptional network. It is of interest to quantify
uncertainty of not knowing accurately reaction rates of underlying biochemical reactions …

Defining distributions of molecule counts produced in the cell can elucidate stochastic
dynamics of the underlying biological circuits. For genetic circuits, only a few distributions of …

Estimating hidden processes from non-linear noisy observations is particularly difficult when
the parameters of these processes are not known. This paper adopts a machine learning …