Evidence has emerged in the last two decades that at the molecular level most chronic
diseases, including cancer, are caused by a dysregulated inflammatory response. The …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers and is the third
highest among cancer related deaths. Despite modest success with therapy such as …

Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial
heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA …

NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

Iron deficiency, with or without anemia, is the most frequent hematological manifestation in
individuals with cancer, and is especially common in patients with colorectal cancer. Iron is a …

Clear cell renal cell carcinoma (ccRCC), a prevalent kidney cancer form characterised by its
invasiveness and heterogeneity, presents challenges in late‐stage prognosis and treatment …

Chronic inflammation as an important epigenetic and environmental factor for putative
tumorigenesis and tumor progression may be associated with specific activation of Toll-like …

Proteasomes are large multicatalytic proteinase complexes located in the cytosol and the
nucleus of eukaryotic cells. The ubiquitin-proteasome system is responsible for the …

Over the centuries, plant extracts have been used to treat various diseases. Until now,
natural products have played an important role in anticancer therapy as there are more than …

Background According to cancer-related microRNA (miRNA) expression microarray
research available in public databases, miR-362 expression is elevated in gastric cancer …