A hitchhiker's guide to diffusion tensor imaging

JM Soares, P Marques, V Alves, N Sousa - Frontiers in neuroscience, 2013 - frontiersin.org
Diffusion Tensor Imaging (DTI) studies are increasingly popular among clinicians and
researchers as they provide unique insights into brain network connectivity. However, in …

Remyelination therapies: a new direction and challenge in multiple sclerosis

JR Plemel, WQ Liu, VW Yong - Nature reviews Drug discovery, 2017 - nature.com
Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …

Design and validation of diffusion MRI models of white matter

IO Jelescu, MD Budde - Frontiers in physics, 2017 - frontiersin.org
Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

White matter damage and cognitive impairment after traumatic brain injury

KM Kinnunen, R Greenwood, JH Powell, R Leech… - Brain, 2011 - academic.oup.com
White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …

Quantification of increased cellularity during inflammatory demyelination

Y Wang, Q Wang, JP Haldar, FC Yeh, M Xie, P Sun… - Brain, 2011 - academic.oup.com
Multiple sclerosis is characterized by inflammatory demyelination and irreversible axonal
injury leading to permanent neurological disabilities. Diffusion tensor imaging demonstrates …

Effect of long-term cannabis use on axonal fibre connectivity

A Zalesky, N Solowij, M Yücel, DI Lubman, M Takagi… - Brain, 2012 - academic.oup.com
Cannabis use typically begins during adolescence and early adulthood, a period when
cannabinoid receptors are still abundant in white matter pathways across the brain …

Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords

EC Klawiter, RE Schmidt, K Trinkaus, HF Liang… - Neuroimage, 2011 - Elsevier
OBJECTIVE: Correlation of diffusion tensor imaging (DTI) with histochemical staining for
demyelination and axonal damage in multiple sclerosis (MS) ex vivo human cervical spinal …

MR diffusion kurtosis imaging for neural tissue characterization

EX Wu, MM Cheung - NMR in Biomedicine, 2010 - Wiley Online Library
In conventional diffusion tensor imaging (DTI), water diffusion distribution is described as a
2nd‐order three‐dimensional (3D) diffusivity tensor. It assumes that diffusion occurs in a free …

[HTML][HTML] Age effects and sex differences in human brain white matter of young to middle-aged adults: A DTI, NODDI, and q-space study

C Kodiweera, AL Alexander, J Harezlak, TW McAllister… - Neuroimage, 2016 - Elsevier
Microstructural changes in human brain white matter of young to middle-aged adults were
studied using advanced diffusion Magnetic Resonance Imaging (dMRI). Multiple shell …

Late effects of high‐dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: converging results from multimodal magnetic resonance …

MB de Ruiter, L Reneman, W Boogerd… - Human brain …, 2012 - Wiley Online Library
The neural substrate underlying cognitive impairments after chemotherapy is largely
unknown. Here, we investigated very late (> 9 years) effects of adjuvant high‐dose …