During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

More information about a person's genetic makeup, drug response, multi-omics response,
and genomic response is now available leading to a gradual shift towards personalized …

In December 2019, a novel severe acute respiratory syndrome (SARS) from a new
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …

Many risk factors for osteoarthritis (OA) have been noted, while gender/sex differences have
been understated. The work aimed to systematically review literature investigating as …

Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

Current knowledge about mechanisms and interventions for pain has largely been derived
from samples that are healthier, wealthier, younger, and more likely to be White than the …

The global burden of cancer is growing and a wide disparity in the incidence, malignancy
and mortality of different types of cancer between each sex has been demonstrated. The sex …

Diabetic kidney disease (DKD) is one of the most serious complications of both type 1
(T1DM) and type 2 diabetes mellitus (T2DM). Current guidelines recommend a personalized …

Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …

The importance of host genetics and demography in coronavirus disease 2019 (COVID-19)
is a crucial aspect of infection, prognosis and associated case fatality rate. Individual genetic …