Tumor-associated macrophages: recent insights and therapies

J Zhou, Z Tang, S Gao, C Li, Y Feng, X Zhou - Frontiers in oncology, 2020 - frontiersin.org
Macrophages, which have functions of engulfing and digesting foreign substances, can
clear away harmful matter, including cellular debris and tumor cells. Based on the condition …

Revolutionizing anti-tumor therapy: unleashing the potential of B cell-derived exosomes

J Xiong, H Chi, G Yang, S Zhao, J Zhang… - Frontiers in …, 2023 - frontiersin.org
B cells occupy a vital role in the functioning of the immune system, working in tandem with T
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …

An immune atlas of clear cell renal cell carcinoma

S Chevrier, JH Levine, VRT Zanotelli, K Silina… - Cell, 2017 - cell.com
Immune cells in the tumor microenvironment modulate cancer progression and are attractive
therapeutic targets. Macrophages and T cells are key components of the microenvironment …

Tissue macrophages: heterogeneity and functions

S Gordon, A Plüddemann - BMC biology, 2017 - Springer
Macrophages are present in all vertebrate tissues, from mid-gestation throughout life,
constituting a widely dispersed organ system. They promote homeostasis by responding to …

Inhaled particulate accumulation with age impairs immune function and architecture in human lung lymph nodes

BB Ural, DP Caron, P Dogra, SB Wells, PA Szabo… - Nature medicine, 2022 - nature.com
Older people are particularly susceptible to infectious and neoplastic diseases of the lung
and it is unclear how lifelong exposure to environmental pollutants affects respiratory …

Macrophage heterogeneity in tissues: phenotypic diversity and functions

S Gordon, A Plüddemann… - Immunological …, 2014 - Wiley Online Library
During development and throughout adult life, macrophages derived from hematopoietic
progenitors are seeded throughout the body, initially in the absence of inflammatory and …

Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties

BB Ural, ST Yeung, P Damani-Yokota, JC Devlin… - Science …, 2020 - science.org
Tissue-resident macrophages are a diverse population of cells that perform specialized
functions including sustaining tissue homeostasis and tissue surveillance. Here, we report …

Kounis syndrome: an update on epidemiology, pathogenesis, diagnosis and therapeutic management

NG Kounis - Clinical Chemistry and Laboratory Medicine (CCLM), 2016 - degruyter.com
Kounis syndrome has been established as a hypersensitivity coronary disorder induced by
various conditions, drugs, environmental exposures, foods and coronary stents. Allergic …

The mannose receptor

L Martinez-Pomares - Journal of leukocyte biology, 2012 - academic.oup.com
Review on mannose receptor as an endocytic receptor in antigen delivery that is co-
expressed with the microRNA miR-511-3p encoded within the Mrc1 gene. The MR is a …

The role of macrophages in the pathogenesis of SARS-CoV-2-associated acute respiratory distress syndrome

A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …