Hydrocephalus is a common disorder of cerebral spinal fluid (CSF) physiology resulting in
abnormal expansion of the cerebral ventricles. Infants commonly present with progressive …

OBJECTIVE Myelomeningocele (MMC), the most severe form of spina bifida, is
characterized by protrusion of the meninges and spinal cord through a defect in the vertebral …

Background Postinfectious hydrocephalus in infants is a major health problem in sub-
Saharan Africa. The conventional treatment is ventriculoperitoneal shunting, but surgeons …

Object Combined endoscopic third ventriculostomy with choroid plexus cauterization
(ETV/CPC) enhances the likelihood of shunt freedom over ETV alone, and thus avoidance of …

OBJECTIVE Endoscopic third ventriculostomy (ETV) is now established as a viable
treatment option for a subgroup of children with hydrocephalus. Here, the authors report …

Object Evidence from the CURE Children's Hospital of Uganda (CCHU) suggests that
treatment for hydrocephalus in infants can be effective and sustainable in a developing …

The burden of infant hydrocephalus in East Africa is significant, with more than 6000 new
cases estimated per year. The majority is caused by neonatal infection, and should thus be …

Introduction The published results of the Management of Myelomeningocele Study (MOMS)
trial in 2011 showed improved outcomes (reduced need for shunting, decreased incidence …

Object The authors have previously reported on the overall improved efficacy of endoscopic
third ventriculostomy (ETV) combined with choroid plexus cauterization (CPC) for infants …

Hydrocephalus, despite its heterogeneous causes, is ultimately a disease of disordered CSF
homeostasis that results in pathological expansion of the cerebral ventricles. Our current …