Osteoarthritis (OA) can be regarded as a chronic, painful and degenerative disease that
affects all tissues of a joint and one of the major endpoints being loss of articular cartilage. In …

Microbiota is just beginning to be recognized as an important player in carcinogenesis and
the interplay among microbes is greater than expected. Pancreatic ductal adenocarcinoma …

Background Rigorous analysis of levels and trends in exposure to leading risk factors and
quantification of their effect on human health are important to identify where public health is …

The human intestinal microbiome plays a major role in human health and diseases,
including colorectal cancer. Colorectal carcinogenesis represents a heterogeneous process …

Recently, bacterial infection causing periodontal disease has attracted considerable
attention as a risk factor for pancreatic cancer. Fusobacterium species is an oral bacterial …

Autoimmune diseases are immune disorders characterized by T cell hyperactivity and B cell
overstimulation leading to overproduction of autoantibodies. Although the pathogenesis of …

MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …

Human gut microbiota is being increasingly recognized as a player in colorectal cancers
(CRCs). Evidence suggests that Fusobacterium nucleatum (F. nucleatum) may contribute to …

The endothelium forms a vast network that dynamically regulates vascular barrier function,
coagulation pathways and vasomotor tone. Microvascular endothelial cells are uniquely …

Osteoarthritis is a progressive joint disease and a major cause of disability for which no
curative therapies are yet available. To identify compounds with potential anti-osteoarthritic …