Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

The 90-kDa molecular chaperone family (which comprises, among other proteins, the 90-
kDa heat-shock protein, hsp90 and the 94-kDa glucose-regulated protein, grp94, major …

A continuous threat to cell function and viability is the contain components of the ubiquitin-
proteasome degraaccumulation in cells of proteins with highly abnormal dative pathway and …

Toward a genetic dissection of the processes involved in aging, a screen for gene mutations
that extend life-span in Drosophila melanogaster was performed. The mutant line …

Introduction Adaptogens are natural compounds or plant extracts that increase adaptability
and survival of organisms under stress. Adaptogens stimulate cellular and organismal …

Huntington's disease (HD) is the most common inherited neurodegenerative disease and is
characterized by uncontrolled excessive motor movements and cognitive and emotional …

In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself
against external stressors from various sources. This defense mechanism probably evolved …

The capacity to moderate internal and external stress is arguably the central function
regulating senescence in whole-animal ageing,,. During ageing, molecular chaperones …

Since their discovery, heat shock proteins (HSPs) have been identified in all domains of life,
which demonstrates their importance and conserved functional role in maintaining protein …

The formation of insoluble protein aggregates in neurons is a hallmark of neurodegenerative
diseases caused by proteins with expanded polyglutamine (polyQ) repeats. However, the …