Unraveling particle formation: From single droplet drying to spray drying and electrospraying

E Boel, R Koekoekx, S Dedroog, I Babkin, MR Vetrano… - Pharmaceutics, 2020 - mdpi.com
Spray drying and electrospraying are well-established drying processes that already have
proven their value in the pharmaceutical field. However, there is currently still a lack of …

Biological activities and solubilization methodologies of naringin

H Jiang, M Zhang, X Lin, X Zheng, H Qi, J Chen… - Foods, 2023 - mdpi.com
Naringin (NG), a natural flavanone glycoside, possesses a multitude of pharmacological
properties, encompassing anti-inflammatory, sedative, antioxidant, anticancer, anti …

The future of poly (2-oxazoline) s

R Hoogenboom - European Polymer Journal, 2022 - Elsevier
Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Stable amorphous solid dispersion of flubendazole with high loading via electrospinning

J Becelaere, E Van Den Broeck, E Schoolaert… - Journal of Controlled …, 2022 - Elsevier
In this work, an important step is taken towards the bioavailability improvement of poorly
water-soluble drugs, such as flubendazole (Flu), posing a challenge in the current …

Soluplus-mediated diosgenin amorphous solid dispersion with high solubility and high stability: development, characterization and oral bioavailability

P Liu, J Zhou, J Chang, X Liu, H Xue… - Drug design …, 2020 - Taylor & Francis
Background and Purpose The traditional Chinese medicine, diosgenin (Dio), has attracted
increasing attention because it possesses various therapeutic effects, including anti-tumor …

Solvent electrospinning amorphous solid dispersions with high itraconazole, celecoxib, mebendazole and fenofibrate drug loading and release potential

J Becelaere, O Frateur, E Schoolaert… - Journal of Controlled …, 2023 - Elsevier
In this work, the feasibility of ultra-high drug loaded amorphous solid dispersions (ASDs) for
the poorly soluble itraconazole, mebendazole and celecoxib via solvent electrospinning in …

Investigation of poly (2-ethyl-2-oxazoline) as a novel extended release polymer for hot-melt extrusion paired with fused deposition modeling 3D printing

S Feng, S Bandari, MA Repka - Journal of Drug Delivery Science and …, 2022 - Elsevier
This study investigates the application of poly (2-ethyl-2-oxazoline)(PEtOx) as the main
matrix for the development of solid oral tablets with extended release profile using hot-melt …

Tunable drug release from fused deposition modelling (FDM) 3D-printed tablets fabricated using a novel extrudable polymer

V Raje, S Palekar, S Banella, K Patel - Pharmaceutics, 2022 - mdpi.com
Three-dimensional (3D) printing is proving to be a pivotal technology for developing
personalized dosage forms with bench to bedside feasibility. Fused deposition modelling …

Chitosan/poly (2-ethyl-2-oxazoline) films with ciprofloxacin for application in vaginal drug delivery

GK Abilova, DB Kaldybekov, GS Irmukhametova… - Materials, 2020 - mdpi.com
Chitosan (CHI) and chitosan/poly (2-ethyl-2-oxazoline)(CHI/POZ)-based films were
prepared by casting from aqueous solutions of polymer blends with different compositions …

Polymer structure and property effects on solid dispersions with haloperidol: Poly (N-vinyl pyrrolidone) and poly (2-oxazolines) studies

X Shan, AC Williams, VV Khutoryanskiy - International Journal of …, 2020 - Elsevier
Abstract Poly (2-methyl-2-oxazoline)(PMOZ), poly (2-propyl-2-oxazoline)(PnPOZ) and poly
(2-isopropyl-2-oxazoline)(PiPOZ) were synthesized by hydrolysis of 50 kDa poly (2-ethyl-2 …