Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases

T Litman - Apmis, 2019 - Wiley Online Library
The current state, tools, and applications of personalized medicine with special emphasis on
inflammatory skin diseases like psoriasis and atopic dermatitis are discussed. Inflammatory …

Targeting phenotypic heterogeneity in benign prostatic hyperplasia

DW Strand, DN Costa, F Francis, WA Ricke… - Differentiation, 2017 - Elsevier
Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to
treat medically, resulting in hundreds of thousands of surgeries performed annually in …

Fluorescence of picrosirius red multiplexed with immunohistochemistry for the quantitative assessment of collagen in tissue sections

KA Wegner, A Keikhosravi… - … of Histochemistry & …, 2017 - journals.sagepub.com
The low cost and simplicity of picrosirius red (PSR) staining have driven its popularity for
collagen detection in tissue sections. We extended the versatility of this method by using …

Comparative evaluation of MS-based metabolomics software and its application to preclinical Alzheimer's disease

L Hao, J Wang, D Page, S Asthana, H Zetterberg… - Scientific reports, 2018 - nature.com
Mass spectrometry-based metabolomics has undergone significant progresses in the past
decade, with a variety of software packages being developed for data analysis. However …

Investigation of the urinary metabolic variations and the application in bladder cancer biomarker discovery

X Liu, X Cheng, X Liu, L He, W Zhang… - … journal of cancer, 2018 - Wiley Online Library
Urine metabolomics have been used to identify biomarkers for clinical diseases. However,
inter‐individual variations and effect factors need to be further evaluated. In our study, we …

Revolutionizing drug discovery; transformative role of machine learning

M Siddiq - BULLET: Jurnal Multidisiplin Ilmu, 2022 - journal.mediapublikasi.id
The use of machine learning in drug discovery is examined in this review article along with
any potential advantages, difficulties, and prospective future developments. The article …

Molecular docking analysis of flavonoid compounds with matrix metalloproteinase-8 for the identification of potential effective inhibitors

A Taherkhani, A Orangi, S Moradkhani… - Letters in Drug …, 2021 - ingentaconnect.com
Background: Matrix metalloproteinase-8 (MMP-8) participates in the degradation of different
types of collagens in the extracellular matrix and basement membrane. Up-regulation of the …

[HTML][HTML] Prostate enlargement and altered urinary function are part of the aging process

TT Liu, S Thomas, DT Mclean, A Roldan-Alzate… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Prostate disease incidence, both benign and malignant, directly correlates with age. Men
under 40 years of age are rarely diagnosed with benign or malignant prostate disease, while …

Recent advances in understanding of Alzheimer's disease progression through mass spectrometry-based metabolomics

J Mill, L Li - Phenomics, 2022 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in the aging population, but
despite extensive research, there is no consensus on the biological cause of AD. While AD …

Metandem: an online software tool for mass spectrometry-based isobaric labeling metabolomics

L Hao, Y Zhu, P Wei, J Johnson, A Buchberger… - Analytica chimica …, 2019 - Elsevier
Mass spectrometry-based stable isotope labeling provides the advantages of multiplexing
capability and accurate quantification but requires tailored bioinformatics tools for data …