Molecular pathways of oral submucous fibrosis and its progression to malignancy

K Gayathri, N Malathi, V Gayathri, PN Adtani… - Archives of oral …, 2023 - Elsevier
Objective The review aims to comprehend various factors engaged in the alteration of
molecular events resulting in Oral submucous fibrosis (OSMF) and its malignant …

An enigmatic pathogenetic mechanism of hypoxia inducible factor-1/2 alpha in the progression of fibrosis of oral submucous fibrosis and its malignant transformation …

R Keerthika, A Chandra, T Jain, N Singh… - Archives of Oral Biology, 2024 - Elsevier
Objective Oral submucous fibrosis is a frequently reported potentially malignant disorder
characterized by fibrosis and a malignant transformation rate of 7–30%. The role of hypoxia …

[PDF][PDF] Immunohistochemical comparison of CD44 and hypoxia inducible Factor‐1 alpha (HIF‐1α) in Oral squamous cell carcinoma and Oral epithelial dysplasia: a …

DEA Salama, A Hasan, GA Balbola, AM Taha… - J Med Chem …, 2024 - researchgate.net
Oral cancer is the 16th most prevalent malignancy and the 15th most common cause of
death worldwide. About 350,000 new cases of oral cancer are detected each year according …

[HTML][HTML] Computational analysis of phytocompounds in Centella asiatica for its antifibrotic and drug-likeness properties-Herb to drug study

K Gayathri, PA Abhinand, V Gayathri, VP Lakshmi… - Heliyon, 2024 - cell.com
Oral submucous fibrosis (OSMF) is a potentially malignant disorder with no permanent cure
that affects the quality of life due to trismus. Computational pharmacology has accelerated …

[PDF][PDF] Oral Submucous Fibrosis Patients Expressed Hypoxia Inducible Factor-1α (HIF-1α) in Saliva: A Biomarker for Detection of Malignant Transformation

N SHAFIQ, S AKRAM, TALI KHAN… - Pakistan Journal of …, 2022 - academia.edu
Objective: Aim of this current study was to determine the malignant transformation
associated with hypoxia inducible factor-1α among patients of oral submucous fibrosis …

The Immunohistochemical Landscape of the Hypoxia-Related Proteins in Oral Squamous Cell Carcinoma

AI Lorenzo Pouso, MÁ González-Moles… - 2022 - Springer
Oral squamous cell carcinoma (OSCC) represents 95% of all cancers of the head and neck
region. Tumour hypoxia, the situation where tumour cells have been deprived of oxygen …

[HTML][HTML] The Study of Expression of Hypoxia-Inducible Factor-1 Alpha (HIF-1 Alpha) and Hypoxia-Inducible Factor-2 Alpha (HIF-2 Alpha) in Oral Squamous Cell …

N Mahapatra, A Panda, K Dash, L Bhuyan, P Mishra… - Cureus, 2023 - ncbi.nlm.nih.gov
Context: Oral cancer is the major cause of mortality and morbidity worldwide. There are
many factors that influence the tumor microenvironment that promotes tumorigenesis …

[PDF][PDF] Salivary expression of HIF-1 α in oral submucous fibrosis

K Iqbal, M Hosein, S Butt, A Razi - Pakistan Journal of Medicine …, 2021 - ojs.zu.edu.pk
Background: Oral submucous fibrosis (OSMF), a chronic debilitating condition distinguished
by juxtaepithelial fibrosis or extensive fibrosis of submucosa and reduced vascularity, results …

[PDF][PDF] 口腔黏膜下纤维性变癌变的研究进展

王雨田, 黄国栋, 刘子建, 刘宏伟 - 中国口腔医学继续教育杂志, 2022 - cndent.com
摘要口腔黏膜下纤维性变(oral submucous fibrosis, OSF) 是一种口腔潜在恶性疾患(oral
potentially malignant disorder, OPMD), 可进展为口腔鳞状细胞癌(oral squamous cell …

[PDF][PDF] Archive of SID. ir

DEA Salama, A Hasan, GA Balbola, AM Taha… - therapy, 2024 - sid.ir
Oral cancer is the 16th most prevalent malignancy and the 15th most common cause of
death worldwide. About 350,000 new cases of oral cancer are detected each year according …