The time and cost of developing new drugs have led many groups to limit their search for
therapeutics to compounds that have previously been approved for human use. Many …

The plasma membrane (PM) performs a plethora of physiological processes, the
coordination of which requires spatial and temporal organization into specialized domains of …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Many viruses interface with the autophagy pathway, a highly conserved process for
recycling cellular components. For three viral infections in which autophagy constituents are …

Eukaryotic cells frequently experience fluctuations of the external and internal environments,
such as changes in nutrient, energy and oxygen sources, and protein folding status, which …

Autophagy is a highly conserved catabolic pathway that is vital for development, cell
survival, and the degradation of dysfunctional organelles and potentially toxic aggregates …

Non-polio enteroviruses are emerging viruses known to cause outbreaks of polio-like
infections in different parts of the world with several cases already reported in Asia Pacific …

To remain competitive, cells exposed to stress of varying duration, rapidity of onset, and
intensity, have to balance their expenditure on growth and proliferation versus stress …

Macroautophagy/autophagy is a highly conserved pathway of cellular degradation and
recycling that maintains cell health during homeostatic conditions and facilitates survival …

This review outlines a literature‐based approach with illustrative examples of drug
repurposing (one molecule, multiple targets), which will be useful in tackling the problem of …