The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …

Acute pancreatitis (AP) is a common acute abdominal disease, 10–20% of which can evolve
into severe AP (SAP) causing significant morbidity and mortality. Bone marrow-derived …

Chronic liver diseases constitute a significant economic, social, and biomedical burden.
Among commonly adopted approaches, only organ transplantation can radically help …

The Hippo pathway plays prominent and widespread roles in various forms of human
carcinogenesis. Specifically, the Yes-associated protein (YAP), a downstream effector of the …

Abstract Nowadays, Mesenchymal stem cells (MSCs) have become one of the most
attractive tools for treating tumors, due to their specific characteristics, the most prominent of …

Pancreatitis is a common gastrointestinal disease with no effective therapeutic options,
particularly for cases of severe acute and chronic pancreatitis (CP). Mesenchymal stromal …

Background and aims It has been previously verified that mesenchymal stromal cells
(MSCs) have a good therapeutic effect on severe acute pancreatitis (SAP) and the potential …

Hepatocellular carcinoma (HCC) is the most common hepatobiliary malignancy with limited
therapeutic options. On the other hand, melatonin is an indoleamine that modulates a variety …

In cancer, mesenchymal stem/stromal cells (MSCs) have been considered as vehicles for
targeted delivery of drugs due to their inherent tropism toward primary and metastatic …

Tumors can invade, compress, and damage nerves, leading to persistent pain and seriously
affecting the quality of life of patients. However, their treatment is challenging. Sensitization …