The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling

B Bottazzi, A Inforzato, M Messa, M Barbagallo… - Journal of …, 2016 - Elsevier
Pentraxins are a superfamily of fluid phase pattern recognition molecules conserved in
evolution and characterized by a cyclic multimeric structure. C-reactive protein (CRP) and …

Circulating tumor necrosis factor‐α levels in non‐alcoholic fatty liver disease: A systematic review and a meta‐analysis

V Potoupni, M Georgiadou… - Journal of …, 2021 - Wiley Online Library
Abstract Background and Aim To synthesize data on circulating tumor necrosis factor (TNF)‐
α levels between patients with histologically confirmed non‐alcoholic fatty liver disease …

The long pentraxin PTX 3: A prototypical sensor of tissue injury and a regulator of homeostasis

M Erreni, AA Manfredi, C Garlanda… - Immunological …, 2017 - Wiley Online Library
Tissue damage frequently occurs. The immune system senses it and enforces homeostatic
responses that lead to regeneration and repair. The synthesis of acute phase molecules is …

Advances in noninvasive biomarkers for nonalcoholic fatty liver disease

GE Gîlcă-Blanariu, DS Budur, DE Mitrică, E Gologan… - Metabolites, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) currently represents one of the most common liver
diseases worldwide. Early diagnosis and disease staging is crucial, since it is mainly …

[PDF][PDF] Pentraxin‐3 modulates lipopolysaccharide‐induced inflammatory response and attenuates liver injury

L Perea, M Coll, L Sanjurjo, D Blaya… - …, 2017 - Wiley Online Library
Acute‐on‐chronic liver injury is characterized by an important inflammatory response
frequently associated with endotoxemia. In this context, acute‐phase proteins such as …

Serum pentraxin 3 as a biomarker of hepatocellular carcinoma in chronic hepatitis B virus infection

H Deng, X Fan, X Wang, L Zeng, K Zhang, X Zhang… - Scientific Reports, 2020 - nature.com
Biomarkers for early diagnosis of hepatocellular carcinoma (HCC) are needed in chronic
hepatitis B virus (HBV) infection, a leading cause of HCC. We evaluated whether …

Controversies and opportunities in the use of inflammatory markers for diagnosis or risk prediction in fatty liver disease

J Lambrecht, F Tacke - Frontiers in Immunology, 2021 - frontiersin.org
In the Western society, non-alcoholic fatty liver disease (NAFLD), characterized by the
excessive accumulation of fat in the liver, represents the most common cause of chronic liver …

Administration of hydro-alcoholic extract of spinach improves oxidative stress and inflammation in high-fat diet-induced NAFLD rats

A Amirinejad, AS Totmaj, F Mardali… - … Medicine and Therapies, 2021 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease
worldwide. The aim of this study was to evaluate the effects of hydro-alcoholic extract of …

Pentraxin 3 and the TyG index as two novel markers to diagnose NAFLD in children

X Ye, J Li, H Wang, J Wu - Disease Markers, 2021 - Wiley Online Library
Background. The diagnosis of NAFLD requires a liver biopsy, which is difficult in children.
This study explored the diagnostic value of pentraxin 3 (PTX‐3) and the triglyceride‐glucose …

Valuable effects of lactobacillus and citicoline on steatohepatitis: role of Nrf2/HO-1 and gut microbiota

AM El-Baz, AM El-Ganiny, D Hellal, HM Anwer… - AMB Express, 2023 - Springer
Non-alcoholic steatohepatitis (NASH) is a more dangerous form of chronic non-alcoholic
fatty liver disease (NAFLD). In the current investigation, the influence of citicoline on high-fat …