Mitochondrial targeted antioxidants as potential therapy for huntington's disease

S Upadhayay, P Kumar - Pharmacological Reports, 2024 - Springer
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by an
expansion in CAG repeat on huntington (Htt) gene, leading to a degeneration of GABAergic …

Insights into AlphaFold's breakthrough in neurodegenerative diseases

H Mubeen, A Masood, A Zafar, ZQ Khan… - Irish Journal of Medical …, 2024 - Springer
Neurodegenerative diseases (ND) are disorders of the central nervous system (CNS)
characterized by impairment in neurons' functions, and complete loss, leading to memory …

A Computational approach to uncover the missense mutations in candidate genes of late-onset Alzheimer's disease

H MUBEEN, A Masood, A Zafar, ZQ Khan, MQ Khan… - 2022 - researchsquare.com
Background Alzheimer's (induced by ultimate demise of nerve cells) is a neurodegenerative
disorder, and experts are still lagging in this disease, owing to the polygenic and multi …