Neuroplasticity is the capacity of neural networks in the brain to alter through development
and rearrangement. It can be classified as structural and functional plasticity. The …

The discovery of prions has challenged dogmas and has revolutionized our understanding
of protein‐misfolding diseases. The concept of self‐propagation via protein conformational …

Synapse loss is the principal cause of cognitive decline in Alzheimer's disease (AD) and
related disorders (ADRD). Synapse development depends on the intricate dynamics of the …

Cofilactin rod pathology, which can initiate synapse loss, has been extensively studied in
rodent neurons, hippocampal slices, and in vivo mouse models of human …

Immune responses in the central nervous system are mediated by microglia, whose
responses to CNS threats can be replicated in vitro to study the role of microglia in the onset …