Hypertension is highly prevalent after the age of 65 years affecting more than 60% of
individuals in developed countries. Today, there is sufficient evidence from clinical trials that …

Chronic kidney disease (CKD) affects over 850 million people globally, and there is an
urgent need to prevent its development and progression. During the last decade, new …

Results The median number of medications was eight; the prevalence of polypharmacy and
hyperpolypharmacy was each 38%. During the observation period (median, 4.8 years), 120 …

Background Elderly patients with chronic kidney disease (CKD) frequently present
comorbidities that put them at risk of polypharmacy and medication-related problems. This …

Diabetic kidney disease and its comorbid conditions, including atherosclerotic
cardiovascular disease, heart failure, diabetes, and obesity, are interconnected conditions …

In patients suffering from moderate-to-severe chronic kidney disease (CKD) or end-stage
renal disease (ESRD), subjected to hemodialysis (HD), pain is very common, but often …

Frailty has been defined as a state of increased vulnerability as a consequence of deficit
accumulation. Frailty screening has not yet been widely implemented into routine …

For the first time in many years, guideline-directed drug therapies have emerged that offer
substantial cardiorenal benefits, improved quality of life and longevity in patients with …

Importance There are limited data for the utility of statins for primary prevention of
atherosclerotic cardiovascular disease (ASCVD) and death in adults with chronic kidney …

Background Deprescribing is essential for reducing inappropriate medication use and
polypharmacy. For a holistic approach, it is essential to know how older adult patients and …