Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes

CF McKenna, HD Stierwalt… - American Journal …, 2024 - journals.physiology.org
Elevated skeletal muscle diacylglycerols (DAG) and ceramides can impair insulin signaling,
and acylcarnitines (acylCN) reflect impaired fatty acid oxidation, thus the intramuscular lipid …

Imprecision nutrition? Intraindividual variability of glucose responses to duplicate presented meals in adults without diabetes

A Hengist, JA Ong, K McNeel, J Guo, KD Hall - The American Journal of …, 2025 - Elsevier
Abstract Background Continuous glucose monitors (CGMs) are used to characterize
postprandial glucose responses and provide personalized dietary advice to minimize …

The Reproducibility and Reliability of Insulin Sensitivity and Secretion Indices in Children and Adolescents

NS Hani, ME Vajravelu, JL Meijer… - Pediatric …, 2024 - Wiley Online Library
Context. Insulin sensitivity and secretion indices can be useful tools in understanding insulin
homeostasis in children at risk for diabetes. There have been few studies examining the …

An algorithm to simulate missing data for mixed meal tolerance test response curves

GJ LaPorte, S Chauff, J Cammack… - The American Journal of …, 2024 - Elsevier
Background Response curves formed by analyte concentrations measured at sampled time
points after consuming a mixed meal are increasingly being used to characterize responses …

Integration of Multiple Big Data Sources for Modeling Precision Nutrition

K Cummiskey, DM Thomas - Precision Nutrition, 2024 - Elsevier
The overarching goal of Precision Nutrition modeling is to identify factors that predict the
individual response to different diets with the aim of using these factors to design …