Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

There is an ongoing threat of epidemic or pandemic diseases that could be caused by
influenza, Ebola or other emerging viruses. It will be difficult and costly to develop new drugs …

Exposure of rats to elevated dietary salt following recovery from acute kidney injury (AKI)
accelerates the transition to chronic kidney disease (CKD), and is dependent on lymphocyte …

Cerebral malaria claims the lives of over 600,000 African children every year. To better
understand the pathogenesis of this devastating disease, we compared the cellular …

Antibodies against two G-protein coupled receptors (GPCRs), angiotensin II type 1 receptor
(AT1R) and endothelin A receptor (ETAR) are among a growing number of autoantibodies …

Abstract Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in
the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a …

Hypertension remains the leading preventable risk factor for stroke and coronary artery
disease, significantly contributing to all-cause global mortality and predisposing patients to …

Central role of IL-17/Th17 immune responses and the gut micr... : Current Opinion in
Gastroenterology Central role of IL-17/Th17 immune responses and the gut microbiota in the …

Abstract Malaria in Pregnancy (MiP) is characterized by placental accumulation of
Plasmodium-infected erythrocytes, intrauterine growth restriction (IUGR) and preterm …

Background Malaria is a parasitic disease that compromises the human host. Currently,
control of the Plasmodium falciparum burden is centered on artemisinin-based combination …