The ever-changing roles of serotonin
Abstract Serotonin (5-HT) has traditional roles as a key neurotransmitter in the central
nervous system and as a regulatory hormone controlling a broad range of physiological …
nervous system and as a regulatory hormone controlling a broad range of physiological …
Mechanisms controlling hormone secretion in human gut and its relevance to metabolism
The homoeostatic regulation of metabolism is highly complex and involves multiple inputs
from both the nervous and endocrine systems. The gut is the largest endocrine organ in our …
from both the nervous and endocrine systems. The gut is the largest endocrine organ in our …
Gut enterochromaffin cells drive visceral pain and anxiety
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents an
important component of chronic visceral pain. For the growing population afflicted by irritable …
important component of chronic visceral pain. For the growing population afflicted by irritable …
[HTML][HTML] Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome
AV Hartstra, V Schüppel, S Imangaliyev… - Molecular …, 2020 - Elsevier
Objective Increasing evidence indicates that intestinal microbiota play a role in diverse
metabolic processes via intestinal butyrate production. Human bariatric surgery data …
metabolic processes via intestinal butyrate production. Human bariatric surgery data …
[HTML][HTML] A focus on enterochromaffin cells among the enteroendocrine cells: localization, morphology, and role
R Rezzani, C Franco, L Franceschetti, M Gianò… - International Journal of …, 2022 - mdpi.com
The intestinal epithelium plays a key role in managing the relationship with the environment,
the internal and external inputs, and their changes. One percent of the gut epithelium is …
the internal and external inputs, and their changes. One percent of the gut epithelium is …
Role of 5‐HT in the enteric nervous system and enteroendocrine cells
NJ Spencer, DJ Keating - British Journal of Pharmacology, 2025 - Wiley Online Library
Since the 1950s, considerable circumstantial evidence had been presented that
endogenous 5‐HT (serotonin) synthesized from within the wall of the gastrointestinal (GI) …
endogenous 5‐HT (serotonin) synthesized from within the wall of the gastrointestinal (GI) …
Neonatal antibiotics have long term sex‐dependent effects on the enteric nervous system
Infants and young children receive the highest exposures to antibiotics globally. Although
there is building evidence that early life exposure to antibiotics increases susceptibility to …
there is building evidence that early life exposure to antibiotics increases susceptibility to …
5-羟色胺与腹泻型肠易激综合征相关性及中医药调控研究进展
苏海霞， 付兆媛， 高永泽， 尉戎戎， 钟建春 - 中国全科医学, 2023 - chinagp.net
5-羟色胺是影响腹泻型肠易激综合征患者胃肠道功能活动的重要脑肠肽. 近年来研究发现5-
羟色胺的合成, 释放, 与受体结合及重摄取等信号传导过程中, 任一环节发生异常均有可能导致 …
羟色胺的合成, 释放, 与受体结合及重摄取等信号传导过程中, 任一环节发生异常均有可能导致 …
Linking serotonin homeostasis to gut function: Nutrition, gut microbiota and beyond
L Jiang, D Han, Y Hao, Z Song, Z Sun… - Critical Reviews in Food …, 2024 - Taylor & Francis
Abstract Serotonin (5-HT) produced by enterochromaffin (EC) cells in the digestive tract is
crucial for maintaining gut function and homeostasis. Nutritional and non-nutritional stimuli …
crucial for maintaining gut function and homeostasis. Nutritional and non-nutritional stimuli …
Advances in brain-gut-microbiome interactions: a comprehensive update on signaling mechanisms, disorders, and therapeutic implications
The complex, bidirectional interactions between the brain, the gut and the gut microbes are
best referred to as the Brain Gut Microbiome system. Animal and clinical studies have …
best referred to as the Brain Gut Microbiome system. Animal and clinical studies have …