Approaches and challenges in SARS-CoV-2 vaccine development
The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this
global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster …
global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster …
Humoral immune responses in COVID-19 patients: a window on the state of the art
G Siracusano, C Pastori, L Lopalco - Frontiers in immunology, 2020 - frontiersin.org
The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …
A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2
Effective countermeasures against the recent emergence and rapid expansion of the 2019
novel coronavirus (SARS-CoV-2) require the development of data and tools to understand …
novel coronavirus (SARS-CoV-2) require the development of data and tools to understand …
[HTML][HTML] Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies
The beginning of 2020 has seen the emergence of COVID-19 outbreak caused by a novel
coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). There is an …
coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). There is an …
Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies
COVID-19 patients elicit strong responses to the nucleocapsid (N) protein of SARS-CoV-2
but binding antibodies are also detected in prepandemic individuals, indicating potential …
but binding antibodies are also detected in prepandemic individuals, indicating potential …
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes
Background The ongoing COVID-19 pandemic has created an urgency to identify novel
vaccine targets for protective immunity against SARS-CoV-2. Early reports identify protective …
vaccine targets for protective immunity against SARS-CoV-2. Early reports identify protective …
S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected …
H Hofmann, K Hattermann, A Marzi… - Journal of …, 2004 - Am Soc Microbiol
The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) causes severe
pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely …
pneumonia with a fatal outcome in approximately 10% of patients. SARS-CoV is not closely …
[HTML][HTML] Immunoinformatics and molecular modeling approach to design universal multi-epitope vaccine for SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmittable
and pathogenic human coronavirus that caused a pandemic situation of acute respiratory …
and pathogenic human coronavirus that caused a pandemic situation of acute respiratory …
The aetiology, origins, and diagnosis of severe acute respiratory syndrome
LLM Poon, Y Guan, JM Nicholls, KY Yuen… - The Lancet infectious …, 2004 - thelancet.com
Severe acute respiratory syndrome (SARS) is a new infectious disease that first emerged in
Guangdong province, China, in November, 2002. A novel coronavirus was later identified in …
Guangdong province, China, in November, 2002. A novel coronavirus was later identified in …
Molecular and biological characterization of human monoclonal antibodies binding to the spike and nucleocapsid proteins of severe acute respiratory syndrome …
EN van den Brink, J Ter Meulen, F Cox… - Journal of …, 2005 - Am Soc Microbiol
Human monoclonal antibodies (MAbs) were selected from semisynthetic antibody phage
display libraries by using whole irradiated severe acute respiratory syndrome (SARS) …
display libraries by using whole irradiated severe acute respiratory syndrome (SARS) …