Animal toxins—Nature's evolutionary-refined toolkit for basic research and drug discovery

V Herzig, B Cristofori-Armstrong, MR Israel… - Biochemical …, 2020 - Elsevier
Venomous animals have evolved toxins that interfere with specific components of their
victim's core physiological systems, thereby causing biological dysfunction that aids in prey …

Antiprotozoal effect of snake venoms and their fractions: A systematic review

ZU Abdullahi, SS Musa, D He, UM Bello - Pathogens, 2021 - mdpi.com
Background: Protozoal infection is a lingering public health issue of great concern, despite
efforts to produce drugs and vaccines against it. Recent breakthrough research has …

[HTML][HTML] Stonefish (Synanceia spp.) Ichthyocrinotoxins: An ecological review and prospectus for future research and biodiscovery

D Lennox-Bulow, M Smout, A Loukas, J Seymour - Toxicon, 2023 - Elsevier
Marine organisms possess a diverse array of unique substances, many with wide ranging
potential for applications in medicine, industry, and other sectors. Stonefish (Synanceia …

[HTML][HTML] A comparison of the venom proteomes and potential therapeutics of 3 African Naja subgenera

BC Offor, LA Piater - Toxicon, 2024 - Elsevier
African cobras (Naja species) represent one of the most encountered medically important
snakes in Africa. They are classified as African spitting (Afronaja subgenus) and non-spitting …

The complex repertoire of Tityus spp. venoms: Advances on their composition and pharmacological potential of their toxins

GA Wiezel, IS Oliveira, MB Reis, IG Ferreira… - Biochimie, 2024 - Elsevier
Animal venoms are a rich and complex source of components, including peptides (such as
neurotoxins, anionic peptides and hypotensins), lipids, proteins (such as proteases …

The Potential Use of Peptides in the Fight against Chagas Disease and Leishmaniasis

H Berhe, M Kumar Cinthakunta Sridhar, M Zerihun… - Pharmaceutics, 2024 - mdpi.com
Chagas disease and leishmaniasis are both neglected tropical diseases that affect millions
of people around the world. Leishmaniasis is currently the second most widespread vector …

Snake venom phospholipases A2 possess a strong virucidal activity against SARS-CoV-2 in vitro and block the cell fusion mediated by spike glycoprotein interaction …

AE Siniavin, MA Nikiforova, SD Grinkina, VA Gushchin… - bioRxiv, 2021 - biorxiv.org
A new coronavirus was recently discovered and named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). In the absence of specific therapeutic and prophylactic agents …

[HTML][HTML] Antihelimentic effect of Androctonus crassicauda scorpion venom against Trichuris arvicolae isolated from Psammomys obesus in Egypt

A Alshammari, FAS Anwar, SAA Mohamed… - Saudi Journal of …, 2023 - Elsevier
Trichuridae family has a genetic and morphological variability between species affecting
rodents, but it is considerably hard to morphologically diagnose species within the genus of …

The Potassium Channel Blocker β-Bungarotoxin from the Krait Bungarus multicinctus Venom Manifests Antiprotozoal Activity

AV Osipov, EG Cheremnykh, RH Ziganshin… - Biomedicines, 2023 - mdpi.com
Protozoal infections are a world-wide problem. The toxicity and somewhat low effectiveness
of the existing drugs require the search for new ways of protozoa suppression. Snake venom …

Comparative Study of the Effect of Snake Venoms on the Growth of Ciliates Tetrahymena pyriformis: Identification of Venoms with High Antiprotozoal Activity

EG Cheremnykh, AV Osipov, VG Starkov… - Doklady Biochemistry …, 2022 - Springer
To search for compounds with antiprotozoal activity, effects of snake venoms on the ciliates
Tetrahymena pyriformis was studied. T. pyriformis from subkingdom of Protozoa, including …