Summary Mycobacterium bovis bacille Calmette-Guérin (BCG), an experimental vaccine
designed to protect cattle from bovine tuberculosis, was administered for the first time to a …

The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …

The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the
ability to induce non-specific cross-protection against pathogens that might be unrelated to …

BACKGROUND Induction of innate immune memory, also termed trained immunity, by the
antituberculosis vaccine bacillus Calmette-Guérin (BCG) contributes to protection against …

Abstract The Bacillus Calmette-Guérin (BCG) vaccine was discovered a century ago and
has since been clinically applicable. BCG can not only be used for the prevention of …

There is a need for safe and effective platform vaccines to protect against coronavirus
disease 2019 (COVID-19) and other infectious diseases. In this randomized, double …

First administered to a human subject as a tuberculosis (TB) vaccine on July 18, 1921,
Bacillus Calmette-Guérin (BCG) has a long history of use for the prevention of TB and later …

The rising incidence of type 1 diabetes (T1D) cannot be ascribed to genetics alone, and
causative environmental triggers and drivers must also be contributing. The prospective …

Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …

Abstract Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome
caused by Coronavirus 2 (SARS-CoV-2). In the light of its rapid global spreading, on 11 …