The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

The role of epithelial damage in the pulmonary immune response

RA Burgoyne, AJ Fisher, LA Borthwick - Cells, 2021 - mdpi.com
Pulmonary epithelial cells are widely considered to be the first line of defence in the lung
and are responsible for coordinating the innate immune response to injury and subsequent …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19

S Makaremi, A Asgarzadeh, H Kianfar… - Inflammation …, 2022 - Springer
A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …

Retinal manifestations in patients with SARS-CoV-2 infection and pathogenetic implications: a systematic review

S Sen, NB Kannan, J Kumar, RP Rajan… - International …, 2022 - Springer
Introduction The pandemic of COVID-19 has been caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus. Apart from respiratory malfunction, COVID-19 …

Respiratory distress in SARS-CoV-2 exposed uninfected neonates followed in the COVID Outcomes in Mother-Infant Pairs (COMP) Study

OM Man, T Azamor, MC Cambou, TL Fuller… - Nature …, 2024 - nature.com
Respiratory distress (RD) has been reported in SARS-CoV-2 exposed uninfected (SEU)
term neonates. Prior studies suggest that prenatal exposure to Coronavirus Disease 19 …

The difference of the inflammatory milieu in MIS-C and severe COVID-19

SL Gurlevik, Y Ozsurekci, E Sağ, P Derin Oygar… - Pediatric …, 2022 - nature.com
Abstract Background Coronavirus disease 19 (COVID-19) may have a severe course in
children. Multisystem inflammatory syndrome in children (MIS-C) is the post-COVID …

IL 33 correlates with COVID-19 severity, radiographic and clinical finding

SS Markovic, M Jovanovic, N Gajovic… - Frontiers in …, 2021 - frontiersin.org
Objective: The increased level of interleukin (IL)-33 is considered as a predictor of severe
coronavirus disease 2019 (COVID-19) infection, but its role at different stages of the disease …

IL-33 and the cytokine storm in COVID-19: from a potential immunological relationship towards precision medicine

F Furci, G Murdaca, A Allegra, L Gammeri… - International Journal of …, 2022 - mdpi.com
Coronavirus SARS-CoV-2 has represented, and still represents, a real challenge from a
clinical, diagnostic and therapeutic point of view. During acute infection, the increased levels …