A gastrointestinal (GI) transmural defect is defined as total rupture of the GI wall, and these
defects can be divided into three categories: perforations, leaks, and fistulas. Surgical …

Background Esophageal perforation is a serious and potentially life-threatening medical
emergency. Given multiple etiologies and varying clinical presentations of the perforated …

Background Leaks from the upper gastrointestinal tract often pose a management
challenge, particularly when surgical treatment has failed or is impossible. Vacuum therapy …

Background and Aims The optimal management of upper GI (UGI) leaks and perforations
remains controversial. Endoscopic vacuum therapy (EVT) is a new alternative endoscopic …

A transmural defect of the upper gastrointestinal (UGI) tract is a life-threatening condition
associated with high morbidity and mortality. Recently, endoscopic vacuum therapy (EVT) …

Background/Aim: Endoscopic vacuum-assisted closure therapy (EVAC) is a promising new
technique for repairing upper gastrointestinal defects of different etiologies. As of 2018 …

Endoscopic negative pressure therapy (ENPT) has been adapted for upper gastrointestinal
tract applications. More than 400 patients have already been treated with ENPT due to …

Recent advancement in endoscopic closure techniques have revolutionized the treatment of
gastrointestinal perforations, leaks and fistulas. Traditionally, these have been managed …

Endoscopic vacuum therapy (EVT) is an increasingly popular treatment option for wall
defects in the upper gastrointestinal tract. After its initial description for the treatment of …

Objectives Endoscopic vacuum therapy (EVT) possesses a unique mechanism of action
providing a less invasive alternative for the management of transmural gastrointestinal …