Recent Advances in Fungal Infections: From Lung Ecology to Therapeutic Strategies With a Focus on Aspergillus spp.

F Palmieri, A Koutsokera, E Bernasconi, P Junier… - Frontiers in …, 2022 - frontiersin.org
Fungal infections are estimated to be the main cause of death for more than 1.5 million
people worldwide annually. However, fungal pathogenicity has been largely neglected. This …

Genome-scale metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome

MH Mirhakkak, X Chen, Y Ni, T Heinekamp… - Nature …, 2023 - nature.com
Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of
people with cystic fibrosis and is one of the most common causes of infectious-disease …

Lung and gut microbiomes in pulmonary aspergillosis: Exploring adjunctive therapies to combat the disease

L Cai, P Gao, Z Wang, C Dai, Y Ning, M Ilkit… - Frontiers in …, 2022 - frontiersin.org
Species within the Aspergillus spp. cause a wide range of infections in humans, including
invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic …

Humoral Immunity Against Aspergillus fumigatus

S Dellière, V Aimanianda - Mycopathologia, 2023 - Springer
Aspergillus fumigatus is one the most ubiquitous airborne opportunistic human fungal
pathogens. Understanding its interaction with host immune system, composed of cellular …

Effects of Helicobacter pylori Infection on the Oral Microbiota of Reflux Esophagitis Patients

T Liang, F Liu, L Liu, Z Zhang, W Dong, S Bai… - Frontiers in Cellular …, 2021 - frontiersin.org
The human oral microbiota plays a vital role in maintaining metabolic homeostasis. To
explore the relationship between Helicobacter pylori (Hp) and reflux esophagitis, we …

[HTML][HTML] Lung microbiota changes during pulmonary Aspergillus fumigatus infection in rats

D Popovic, J Kulas, D Tucovic, AP Aleksandrov… - Microbes and …, 2023 - Elsevier
Since the realization that the lungs are not sterile but are normally inhabited by various
bacterial species, studies have been conducted to define healthy lung microbiota and to …

Clinical identification and microbiota analysis of Chlamydia psittaci- and Chlamydia abortus- pneumonia by metagenomic next-generation sequencing

G Xie, Q Hu, X Cao, W Wu, P Dai, W Guo… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Recently, the incidence of chlamydial pneumonia caused by rare pathogens
such as C. psittaci or C. abortus has shown a significant upward trend. The non-specific …

Gut-Derived Short-Chain Fatty Acids and Macrophage Modulation: Exploring Therapeutic Potentials in Pulmonary Fungal Infections

Q Xie, Q Li, H Fang, R Zhang, H Tang… - Clinical Reviews in Allergy …, 2024 - Springer
Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate
immune cell functions, particularly macrophages. This review explores the potential …

Coccidioidomycosis and host microbiome interactions: What we know and what we can infer from other respiratory infections

S Tejeda-Garibay, KK Hoyer - Journal of Fungi, 2023 - mdpi.com
Between 70 and 80% of Valley fever patients receive one or more rounds of antibiotic
treatment prior to accurate diagnosis with coccidioidomycosis. Antibiotic treatment and …

From the nose to the lungs: the intricate journey of airborne pathogens amid commensal bacteria

C Costantini, E Nunzi, L Romani - American Journal of …, 2022 - journals.physiology.org
The recent COVID-19 pandemic has dramatically brought the pitfalls of airborne pathogens
to the attention of the scientific community. Not only viruses but also bacteria and fungi may …